Toll-like receptors (TLRs)

Toll-like receptors (TLRs) are a class of proteins

Endosomal Toll-Like Receptors (TLRs) mediate enhancement of IL-17A production triggered by Epstein-Barr virus (EBV) DNA in mice.

Endosomal Toll-Like Receptors (TLRs) mediate enhancement of IL-17A production triggered by Epstein-Barr virus (EBV) DNA in mice.

EBV has long-been associated with autoimmune disorders. We have previously shown that EBV DNA increases the production of IL-17A in mice. These properties may play a role in EBV association with autoimmune diseases. The purpose of this study was to explain the mechanism of EBV DNA in which modulate the levels of IL-17A in mice.To study the potential role of endosomal receptors in the detection of EBV DNA, chloroquine, endosomal maturation inhibitors, used to treat mice peripheral blood mononuclear cells (PBMC) in the presence or absence of EBV DNA. IL-17A levels were then assessed by ELISA.

Furthermore, to determine whether TLR3, 7 or 9 play a role in this pathway, a specific inhibitor used for these TLRs in both the rat PBMC and in vivo in BALB / c mice were treated with viral DNA; the level of IL-17A-17A then equal assessed.IL enhanced production of rat PBMCs cultured with EBV DNA; Pre-incubation of PBMC with chloroquine significantly reduce production.

When the cells were cultured with EBV DNA and TLR3, 7 or 9 inhibitor, a significant reduction in levels of IL-17A is detected. The same reduction in the production of IL-17A-induced EBV DNA in mice was observed when the animals were treated with TLR inhibitors.Endosomal TLRs appear to be involved in recognizing EBV DNA and then trigger the production of IL-17A in mice. The EBV is targeting this receptor positive subjects with delayed investigation of autoimmunity may be useful to assess whether they play the same role in humans.

Endosomal Toll-Like Receptors (TLRs) mediate enhancement of IL-17A production triggered by Epstein-Barr virus (EBV) DNA in mice.
Endosomal Toll-Like Receptors (TLRs) mediate enhancement of IL-17A production triggered by Epstein-Barr virus (EBV) DNA in mice.

MPMBP down-regulates Toll-like receptor (TLR) 2 ligand-induced production of proinflammatory cytokines by inhibiting NF-kB but not AP-1 activation.

MPMBP is a non-nitrogen-containing bisphosphonates new (non-NBP), which has an anti-bone resorptive activity and side chain antioxidants. This study aimed to assess the effect of MPMBP on the production of proinflammatory cytokines and chemokines by macrophage-like cell line, J774.1, in the presence of Toll-like receptor (TLR) agonist.

J774.1 cells were pretreated with or without MPMBP for 5 minutes, then incubated with or without Pam3Cys-Ser- (Lys) 4 (Pam3CSK4, TLR2 agonist) or lipid A (TLR4 agonist) for 24 hours. MPMBP down-regulated TLR2 ligand-induced production of IL-6, MCP-1, MIP-1α and TNF-α, but not TLR4 ligand-induced production of proinflammatory cytokines, and cytotoxic to cells J774.1. Cu-CPT22, TLR2 antagonist, down-regulated Pam3CSK4-induced production of IL-6, MCP-1 and MIP-1α, but not TNF-α. MPMBP inhibiting the translocation of NF-kB p65, but not p50, RelB, or p52 and inhibits the activation of JNK, but not p38 MAPK or ERK, in cells stimulated with Pam3CSK4 J774.1. Additionally, MPMBP not down-regulate AP-1 activation in cells stimulated with Pam3CSK4 J774.1 or lipid A. Our findings suggest that MPMBP inhibits the production of proinflammatory cytokines in cell J774.1 by pressing the activation of NF-kB p65 in TLR2, but not TLR4, track.


blocking the right of pulses like receptor (TLR) activation during development of the disease have been reported to have an inhibitory effect on the pathogenesis of rheumatoid arthritis (RA). We tested whether TLR4 inhibitor TAK-242 has potential as a drug for arthritis arthritis.The therapeutic effect of TAK-242 was tested in vitro using human rheumatoid fibroblast-like synoviocyte (FLS) MH7A lines or primary human FLS and adjuvant-induced arthritis (AIA) rats model.

CD284 / TLR4(TLR4/230) Antibody

BNC430230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF543 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC430230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF543 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC050230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF405M conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC050230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF405M conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC550230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF555 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC550230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF555 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC800230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF680 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC800230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF680 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC610230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF660R conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC610230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF660R conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCP0230-250 250uL
EUR 459.6
Description: Primary antibody against CD284 / TLR4(TLR4/230), PerCP conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCR0230-250 250uL
EUR 459.6
Description: Primary antibody against CD284 / TLR4(TLR4/230), RPE conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCA0230-250 250uL
EUR 459.6
Description: Primary antibody against CD284 / TLR4(TLR4/230), APC conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCAP0230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCAP0230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCH0230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCH0230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

TLR4

E8ER1706-43 100ul
EUR 275
Description: Available in various conjugation types.

TLR4

CSB-CL023603HU 10 μg plasmid + 200μl Glycerol Ask for price

TLR4

MBS129143-002mL 0.02mL
EUR 200

TLR4

MBS129143-005mL 0.05mL
EUR 255

TLR4

MBS129143-01mL 0.1mL
EUR 345

TLR4

MBS129143-02mL 0.2mL
EUR 545

TLR4

MBS129143-5x02mL 5x0.2mL
EUR 2265

TLR4

MBS8565241-01mL 0.1mL
EUR 345

TLR4

MBS8565241-01mLAF405L 0.1mL(AF405L)
EUR 565

TLR4

MBS8565241-01mLAF405S 0.1mL(AF405S)
EUR 565

TLR4

MBS8565241-01mLAF610 0.1mL(AF610)
EUR 565

TLR4

MBS8565241-01mLAF635 0.1mL(AF635)
EUR 565

TLR4

MBS8535197-01mL 0.1mL
EUR 305

TLR4

MBS8535197-01mLAF405L 0.1mL(AF405L)
EUR 565

TLR4

MBS8535197-01mLAF405S 0.1mL(AF405S)
EUR 565

TLR4

MBS8535197-01mLAF610 0.1mL(AF610)
EUR 565

TLR4

MBS8535197-01mLAF635 0.1mL(AF635)
EUR 565

TLR4

MBS8535442-01mL 0.1mL
EUR 325

TLR4

MBS8535442-01mLAF405L 0.1mL(AF405L)
EUR 565

TLR4

MBS8535442-01mLAF405S 0.1mL(AF405S)
EUR 565

TLR4

MBS8535442-01mLAF610 0.1mL(AF610)
EUR 565

TLR4

MBS8535442-01mLAF635 0.1mL(AF635)
EUR 565

TLR4

MBS553623-0005mg 0.005mg
EUR 210

TLR4

MBS553623-0025mg 0.025mg
EUR 290

TLR4

MBS553623-1mg 1mg
EUR 3285

CD284 / TLR4(TLR4/230), 0.2mg/mL

BNUB0230-100 100uL
EUR 225
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

CD284 / TLR4(TLR4/230), 0.2mg/mL

BNUB0230-500 500uL
EUR 485
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

CD284 / TLR4(TLR4/230), 1mg/mL

BNUM0230-50 50uL
EUR 396
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

TLR4 siRNA

20-abx905595
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

TLR4-C34

555792 50.0mg
EUR 650

TLR4 siRNA

20-abx936895
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

TLR4 siRNA

20-abx936896
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

TLR4/CD284

GT15235 100 ug
EUR 631.2

TLR4 Peptide

3139P 0.05 mg
EUR 197.7
Description: (CT) TLR4 peptide

TLR4 Peptide

3141P 0.05 mg
EUR 197.7
Description: (NT) TLR4 peptide

TLR4 Peptide

MBS152123-005mg 0.05mg
EUR 175

TLR4 Peptide

MBS152123-5x005mg 5x0.05mg
EUR 770

TLR4 Peptide

MBS152670-005mg 0.05mg
EUR 175

TLR4 Peptide

MBS152670-5x005mg 5x0.05mg
EUR 770

TLR4 Plasmid

PVT7122 2ug
EUR 182

TLR4 antibody

20R-1503 100 ug
EUR 807.6
Description: Rabbit polyclonal TLR4 antibody

TLR4 antibody

20R-1505 100 ug
EUR 807.6
Description: Rabbit polyclonal TLR4 antibody

TLR4 Antibody

24193-100ul 100ul
EUR 468

TLR4 Antibody

24194 100ul
EUR 479

TLR4 Antibody

24194-100ul 100ul
EUR 468

TLR4 Antibody

3251-100 each
EUR 405.6

TLR4 Antibody

3253-100 each
EUR 392.4

TLR4 Antibody

3253-30T each
EUR 175.2

TLR4 Antibody

3139-002mg 0.02 mg
EUR 206.18
Description: TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

TLR4 Antibody

3139-01mg 0.1 mg
EUR 523.7
Description: TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

TLR4 Antibody

3141-002mg 0.02 mg
EUR 206.18
Description: TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

TLR4 Antibody

3141-01mg 0.1 mg
EUR 523.7
Description: TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

TLR4 Antibody

35463 100ul
EUR 479

TLR4 Antibody

35463-100ul 100ul
EUR 468

TLR4 Antibody

35577 100ul
EUR 319

TLR4 Antibody

35577-100ul 100ul
EUR 302.4

TLR4 Antibody

1-CSB-PA776633
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:50-1:200

TLR4 Antibody

E035577 100μg/100μl
EUR 255
Description: Available in various conjugation types.

TLR4 antibody

E18-7017-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

TLR4 antibody

E18-7017-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

TLR4 Antibody

1-CSB-PA902590
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

TLR4 Antibody

1-CSB-PA023603GA01HU
  • Ask for price
  • Ask for price
  • 150ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse, Rat, Bovin. This antibody is Unconjugated. Tested in the following application: ELISA, WB

TLR4 Antibody

E8RT1620 100ul
EUR 225
Description: Available in various conjugation types.

TLR4 Antibody

E911226 100ul
EUR 255
Description: Available in various conjugation types.

TLR4 Antibody

E95258 100μg
EUR 255
Description: Available in various conjugation types.

TLR4 antibody

70R-14023 100 ug
EUR 482
Description: Affinity purified Rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-11717 100 ug
EUR 371
Description: Rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-11719 100 ug
EUR 357
Description: Rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-20849 50 ul
EUR 289
Description: Rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-9659 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-9688 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal TLR4 antibody

TLR4 Antibody

AF7017 200ul
EUR 540

TLR4 Antibody

AF7017-100ul 100ul
EUR 350

TLR4 Antibody

AF7017-200ul 200ul
EUR 450

TLR4 Antibody

AF7017-50ul 50ul
EUR 250

TLR4 Antibody

1-CSB-PA585936
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:50-1:200

TLR4 Antibody

1-CSB-PA237733
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

TLR4 Antibody

1-CSB-PA080181
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1:200-500.ELISA:1/10000

TLR4 Antibody

1-CSB-PA001434
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000

TLR4 antibody

ABF7017 100ug
EUR 325

TLR4 Antibody

F44373-0.08ML 0.08 ml
EUR 140.25
Description: TLR4, a type I membrane protein that belongs to the Toll-like receptor family, cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response TLR4 Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR. TLR4 binds to LY96 via the extracellular domain, and to MyD88 and TIRAP via their respective TIR domains. The protein contains 19 leucine-rich (LRR) repeats, and It is highly expressed in heart, spleen, lung and muscle. Lower levels are found in liver and kidney. Interstrain analyses reveal that TLR4 is a polymorphic protein and that the extracellular domain is far more variable than the cytoplasmic domain, which is variable at the C-terminal.

TLR4 Antibody

F44373-0.4ML 0.4 ml
EUR 322.15
Description: TLR4, a type I membrane protein that belongs to the Toll-like receptor family, cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response TLR4 Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR. TLR4 binds to LY96 via the extracellular domain, and to MyD88 and TIRAP via their respective TIR domains. The protein contains 19 leucine-rich (LRR) repeats, and It is highly expressed in heart, spleen, lung and muscle. Lower levels are found in liver and kidney. Interstrain analyses reveal that TLR4 is a polymorphic protein and that the extracellular domain is far more variable than the cytoplasmic domain, which is variable at the C-terminal.

TLR4 Antibody

F51856-0.08ML 0.08 ml
EUR 140.25
Description: TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.

TLR4 Antibody

F51856-0.4ML 0.4 ml
EUR 322.15
Description: TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.

TLR4 Antibody

GWB-30A958 0.1 mg Ask for price

TLR4 Antibody

GWB-B225A1 0.05 mg Ask for price

TLR4 Antibody

GWB-F07135 0.05 mg Ask for price

TLR4 Antibody

GWB-MV474F 50ug Ask for price

TLR4 Antibody

GWB-MV508D 50ug Ask for price

TLR4 Antibody

V8385-100UG 100 ug
EUR 349.3
Description: This MAb reacts with human Toll-like receptor 4 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V8385-20UG 20 ug
EUR 153.3
Description: This MAb reacts with human Toll-like receptor 4 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V8385SAF-100UG 100 ug
EUR 349.3
Description: This MAb reacts with human Toll-like receptor 4 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V2897-100UG 100 ug
EUR 424.15
Description: This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V2897-20UG 20 ug
EUR 186.15
Description: This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V2897SAF-100UG 100 ug
EUR 424.15
Description: This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

MBS7124864-005mL 0.05mL
EUR 190

TLR4 Antibody

MBS7124864-01mL 0.1mL
EUR 270

TLR4 Antibody

MBS7124864-5x01mL 5x0.1mL
EUR 1205

TLR4 Antibody

MBS7124865-005mL 0.05mL
EUR 190

TLR4 Antibody

MBS7124865-01mL 0.1mL
EUR 270

TLR4 Antibody

MBS7124865-5x01mL 5x0.1mL
EUR 1205

TLR4 Antibody

MBS7118747-005mg 0.05mg
EUR 150

TLR4 Antibody

MBS7118747-01mg 0.1mg
EUR 190

TLR4 Antibody

MBS7118747-5x01mg 5x0.1mg
EUR 845

TLR4 Antibody

MBS7121859-005mg 0.05mg
EUR 150

TLR4 Antibody

MBS7121859-01mg 0.1mg
EUR 190

TLR4 Antibody

MBS7121859-5x01mg 5x0.1mg
EUR 845

TLR4 Antibody

MBS7123168-005mL 0.05mL
EUR 190

TLR4 Antibody

MBS7123168-01mL 0.1mL
EUR 270

TLR4 Antibody

MBS7123168-5x01mL 5x0.1mL
EUR 1205

TLR4 Antibody

MBS7123169-005mL 0.05mL
EUR 190

TLR4 Antibody

MBS7123169-01mL 0.1mL
EUR 270

TLR4 Antibody

MBS7123169-5x01mL 5x0.1mL
EUR 1205

TLR4 Antibody

MBS9400701-01mL 0.1mL
EUR 495

TLR4 Antibody

MBS9400701-5x01mL 5x0.1mL
EUR 2075

TLR4 Antibody

MBS9401366-01mL 0.1mL
EUR 495

TLR4 Antibody

MBS9401366-5x01mL 5x0.1mL
EUR 2075

TLR4 Antibody

MBS9410302-01mL 0.1mL
EUR 305

TLR4 Antibody

MBS9410302-5x01mL 5x0.1mL
EUR 1230

TLR4 Antibody

MBS9410836-01mL 0.1mL
EUR 420

TLR4 Antibody

MBS9410836-5x01mL 5x0.1mL
EUR 1740

TLR4 Antibody

MBS805758-01mg 0.1mg
EUR 480

TLR4 antibody

MBS8512516-005mg 0.05mg
EUR 235

TLR4 antibody

MBS8512516-01mg 0.1mg
EUR 305

TLR4 antibody

MBS8512516-01mLAF405M 0.1mL(AF405M)
EUR 465

TLR4 antibody

MBS8512516-01mLAF546 0.1mL(AF546)
EUR 465

TLR4 antibody

MBS8512516-01mLAF750 0.1mL(AF750)
EUR 465

TLR4 Antibody

MBS8501217-01mg 0.1mg
EUR 325

TLR4 Antibody

MBS8501217-01mLAF405L 0.1mL(AF405L)
EUR 565

TLR4 Antibody

MBS8501217-01mLAF405S 0.1mL(AF405S)
EUR 565

TLR4 Antibody

MBS8501217-01mLAF610 0.1mL(AF610)
EUR 565

TAK-242 dose dependency inhibit the expression of an increase in IL-6, IL-8, MMP-1 and VEGF in LPS-stimulated cells MH7A.

May 2024
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  

Categories

Recent Posts

Tags