Toll-like receptors (TLRs)

Toll-like receptors (TLRs) are a class of proteins

Endosomal Toll-Like Receptors (TLRs) mediate enhancement of IL-17A production triggered by Epstein-Barr virus (EBV) DNA in mice.

Endosomal Toll-Like Receptors (TLRs) mediate enhancement of IL-17A production triggered by Epstein-Barr virus (EBV) DNA in mice.

EBV has long-been associated with autoimmune disorders. We have previously shown that EBV DNA increases the production of IL-17A in mice. These properties may play a role in EBV association with autoimmune diseases. The purpose of this study was to explain the mechanism of EBV DNA in which modulate the levels of IL-17A in mice.To study the potential role of endosomal receptors in the detection of EBV DNA, chloroquine, endosomal maturation inhibitors, used to treat mice peripheral blood mononuclear cells (PBMC) in the presence or absence of EBV DNA. IL-17A levels were then assessed by ELISA.

Furthermore, to determine whether TLR3, 7 or 9 play a role in this pathway, a specific inhibitor used for these TLRs in both the rat PBMC and in vivo in BALB / c mice were treated with viral DNA; the level of IL-17A-17A then equal assessed.IL enhanced production of rat PBMCs cultured with EBV DNA; Pre-incubation of PBMC with chloroquine significantly reduce production.

When the cells were cultured with EBV DNA and TLR3, 7 or 9 inhibitor, a significant reduction in levels of IL-17A is detected. The same reduction in the production of IL-17A-induced EBV DNA in mice was observed when the animals were treated with TLR inhibitors.Endosomal TLRs appear to be involved in recognizing EBV DNA and then trigger the production of IL-17A in mice. The EBV is targeting this receptor positive subjects with delayed investigation of autoimmunity may be useful to assess whether they play the same role in humans.

Endosomal Toll-Like Receptors (TLRs) mediate enhancement of IL-17A production triggered by Epstein-Barr virus (EBV) DNA in mice.
Endosomal Toll-Like Receptors (TLRs) mediate enhancement of IL-17A production triggered by Epstein-Barr virus (EBV) DNA in mice.

MPMBP down-regulates Toll-like receptor (TLR) 2 ligand-induced production of proinflammatory cytokines by inhibiting NF-kB but not AP-1 activation.

MPMBP is a non-nitrogen-containing bisphosphonates new (non-NBP), which has an anti-bone resorptive activity and side chain antioxidants. This study aimed to assess the effect of MPMBP on the production of proinflammatory cytokines and chemokines by macrophage-like cell line, J774.1, in the presence of Toll-like receptor (TLR) agonist.

J774.1 cells were pretreated with or without MPMBP for 5 minutes, then incubated with or without Pam3Cys-Ser- (Lys) 4 (Pam3CSK4, TLR2 agonist) or lipid A (TLR4 agonist) for 24 hours. MPMBP down-regulated TLR2 ligand-induced production of IL-6, MCP-1, MIP-1α and TNF-α, but not TLR4 ligand-induced production of proinflammatory cytokines, and cytotoxic to cells J774.1. Cu-CPT22, TLR2 antagonist, down-regulated Pam3CSK4-induced production of IL-6, MCP-1 and MIP-1α, but not TNF-α. MPMBP inhibiting the translocation of NF-kB p65, but not p50, RelB, or p52 and inhibits the activation of JNK, but not p38 MAPK or ERK, in cells stimulated with Pam3CSK4 J774.1. Additionally, MPMBP not down-regulate AP-1 activation in cells stimulated with Pam3CSK4 J774.1 or lipid A. Our findings suggest that MPMBP inhibits the production of proinflammatory cytokines in cell J774.1 by pressing the activation of NF-kB p65 in TLR2, but not TLR4, track.


blocking the right of pulses like receptor (TLR) activation during development of the disease have been reported to have an inhibitory effect on the pathogenesis of rheumatoid arthritis (RA). We tested whether TLR4 inhibitor TAK-242 has potential as a drug for arthritis arthritis.The therapeutic effect of TAK-242 was tested in vitro using human rheumatoid fibroblast-like synoviocyte (FLS) MH7A lines or primary human FLS and adjuvant-induced arthritis (AIA) rats model.

CD284 / TLR4(TLR4/230) Antibody

BNC800230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF680 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC810230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF680R conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC810230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF680R conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC940230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF594 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC940230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF594 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC700230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF770 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC700230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF770 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC880230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF488A conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC880230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF488A conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC430230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF543 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC430230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF543 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC400230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF640R conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC400230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF640R conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC050230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF405M conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC050230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF405M conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCB0230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Biotin conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCB0230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Biotin conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCAP0230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCAP0230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCR0230-250 250uL
EUR 459.6
Description: Primary antibody against CD284 / TLR4(TLR4/230), RPE conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCP0230-250 250uL
EUR 459.6
Description: Primary antibody against CD284 / TLR4(TLR4/230), PerCP conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNUM0230-50 50uL
EUR 474
Description: Primary antibody against CD284 / TLR4(TLR4/230), 1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCH0230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNCH0230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNUB0230-100 100uL
EUR 250.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), Concentration: 0.2mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNUB0230-500 500uL
EUR 549.6
Description: Primary antibody against CD284 / TLR4(TLR4/230), Concentration: 0.2mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC040230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF405S conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC040230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF405S conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC550230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF555 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC550230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF555 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC610230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF660R conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC610230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF660R conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC680230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF568 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC680230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF568 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC470230-100 100uL
EUR 238.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF647 conjugate, Concentration: 0.1mg/mL

CD284 / TLR4(TLR4/230) Antibody

BNC470230-500 500uL
EUR 652.8
Description: Primary antibody against CD284 / TLR4(TLR4/230), CF647 conjugate, Concentration: 0.1mg/mL

TLR4 siRNA

20-abx905595
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

TLR4 siRNA

20-abx936895
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

TLR4 siRNA

20-abx936896
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

TLR4/CD284

GT15235 100 ug
EUR 631.2

TLR4 Peptide

3139P 0.05 mg
EUR 197.7
Description: (CT) TLR4 peptide

TLR4 Peptide

3141P 0.05 mg
EUR 197.7
Description: (NT) TLR4 peptide

TLR4 Plasmid

PVT7122 2 ug
EUR 319.2

TLR4 Antibody

24193-100ul 100ul
EUR 468

TLR4 Antibody

24194-100ul 100ul
EUR 468

TLR4 antibody

20R-1503 100 ug
EUR 807.6
Description: Rabbit polyclonal TLR4 antibody

TLR4 antibody

20R-1505 100 ug
EUR 807.6
Description: Rabbit polyclonal TLR4 antibody

TLR4 Antibody

3139-002mg 0.02 mg
EUR 206.18
Description: TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

TLR4 Antibody

3139-01mg 0.1 mg
EUR 523.7
Description: TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

TLR4 Antibody

3141-002mg 0.02 mg
EUR 206.18
Description: TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

TLR4 Antibody

3141-01mg 0.1 mg
EUR 523.7
Description: TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

TLR4 antibody

70R-9659 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-9688 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal TLR4 antibody

TLR4 Antibody

AF7017 200ul
EUR 540

TLR4 antibody

70R-11717 100 ug
EUR 523.2
Description: Rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-11719 100 ug
EUR 501.6
Description: Rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-14023 100 ug
EUR 366
Description: Affinity purified Rabbit polyclonal TLR4 antibody

TLR4 antibody

70R-20849 50 ul
EUR 522
Description: Rabbit polyclonal TLR4 antibody

TLR4 Antibody

35463-100ul 100ul
EUR 468

TLR4 Antibody

35577-100ul 100ul
EUR 302.4

TLR4 Antibody

3251-100 each
EUR 405.6

TLR4 Antibody

3253-100 each
EUR 392.4

TLR4 Antibody

3253-30T each
EUR 175.2

TLR4 antibody

ABF7017 100 ug
EUR 525.6

TLR4 Antibody

1-CSB-PA237733
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

TLR4 Antibody

1-CSB-PA080181
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1:200-500.ELISA:1/10000

TLR4 Antibody

1-CSB-PA902590
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

TLR4 Antibody

1-CSB-PA023603GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse, Rat, Bovin. This antibody is Unconjugated. Tested in the following application: ELISA, WB

TLR4 Antibody

1-CSB-PA585936
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:50-1:200

TLR4 Antibody

1-CSB-PA776633
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:50-1:200

TLR4 Antibody

1-CSB-PA001434
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR4. Recognizes TLR4 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000

TLR4 Antibody

F51856-0.08ML 0.08 ml
EUR 140.25
Description: TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.

TLR4 Antibody

F51856-0.4ML 0.4 ml
EUR 322.15
Description: TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.

TLR4 Antibody

F44373-0.08ML 0.08 ml
EUR 140.25
Description: TLR4, a type I membrane protein that belongs to the Toll-like receptor family, cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response TLR4 Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR. TLR4 binds to LY96 via the extracellular domain, and to MyD88 and TIRAP via their respective TIR domains. The protein contains 19 leucine-rich (LRR) repeats, and It is highly expressed in heart, spleen, lung and muscle. Lower levels are found in liver and kidney. Interstrain analyses reveal that TLR4 is a polymorphic protein and that the extracellular domain is far more variable than the cytoplasmic domain, which is variable at the C-terminal.

TLR4 Antibody

F44373-0.4ML 0.4 ml
EUR 322.15
Description: TLR4, a type I membrane protein that belongs to the Toll-like receptor family, cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response TLR4 Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR. TLR4 binds to LY96 via the extracellular domain, and to MyD88 and TIRAP via their respective TIR domains. The protein contains 19 leucine-rich (LRR) repeats, and It is highly expressed in heart, spleen, lung and muscle. Lower levels are found in liver and kidney. Interstrain analyses reveal that TLR4 is a polymorphic protein and that the extracellular domain is far more variable than the cytoplasmic domain, which is variable at the C-terminal.

TLR4 antibody

PAab09837 100 ug
EUR 463.2

TLR4 Antibody

V2897-100UG 100 ug
EUR 349.3
Description: This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V2897-20UG 20 ug
EUR 153.3
Description: This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V2897SAF-100UG 100 ug
EUR 349.3
Description: This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V8385-100UG 100 ug
EUR 349.3
Description: This MAb reacts with human Toll-like receptor 4 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V8385-20UG 20 ug
EUR 153.3
Description: This MAb reacts with human Toll-like receptor 4 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Antibody

V8385SAF-100UG 100 ug
EUR 349.3
Description: This MAb reacts with human Toll-like receptor 4 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

TLR4 Rabbit pAb

A11226-100ul 100 ul
EUR 369.6

TLR4 Rabbit pAb

A11226-200ul 200 ul
EUR 550.8

TLR4 Rabbit pAb

A11226-20ul 20 ul
EUR 219.6

TLR4 Rabbit pAb

A11226-50ul 50 ul
EUR 267.6

TLR4 Rabbit pAb

A17436-100ul 100 ul
EUR 369.6

TLR4 Rabbit pAb

A17436-200ul 200 ul
EUR 550.8

TLR4 Rabbit pAb

A17436-20ul 20 ul
EUR 219.6

TLR4 Rabbit pAb

A17436-50ul 50 ul
EUR 267.6

TLR4 Rabbit pAb

A2464-100ul 100 ul
EUR 369.6

TLR4 Rabbit pAb

A2464-200ul 200 ul
EUR 550.8

TLR4 Rabbit pAb

A2464-20ul 20 ul Ask for price

TLR4 Rabbit pAb

A2464-50ul 50 ul Ask for price

TLR4 Rabbit pAb

A0007-100ul 100 ul
EUR 369.6

TLR4 Rabbit pAb

A0007-200ul 200 ul
EUR 550.8

TLR4 Rabbit pAb

A0007-20ul 20 ul
EUR 219.6

TLR4 Rabbit pAb

A0007-50ul 50 ul
EUR 267.6

TLR4 Rabbit pAb

A5258-100ul 100 ul
EUR 369.6

TLR4 Rabbit pAb

A5258-200ul 200 ul
EUR 550.8

TLR4 Rabbit pAb

A5258-20ul 20 ul
EUR 219.6

TLR4 Rabbit pAb

A5258-50ul 50 ul
EUR 267.6

anti- TLR4 antibody

FNab08727 100µg
EUR 606.3
Description: Antibody raised against TLR4

anti- TLR4 antibody

FNab09837 100µg
EUR 658.5
Description: Antibody raised against TLR4

TLR4 cloning plasmid

CSB-CL023603HU-10ug 10ug
EUR 978
Description: A cloning plasmid for the TLR4 gene.

TLR4 Blocking Peptide

AF7017-BP 1mg
EUR 234

TLR4 Blocking Peptide

33R-10686 50 ug
EUR 229.2
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TLR4 antibody, catalog no. 70R-11719

TLR4 Blocking Peptide

33R-4969 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TLR4 antibody, catalog no. 70R-9659

TLR4 Blocking Peptide

3253BP-50 each
EUR 183.6

Recombinant human TLR4

P2006 100ug Ask for price
Description: Recombinant protein for human TLR4

Polyclonal TLR4 Antibody

APG03000G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR4 . This antibody is tested and proven to work in the following applications:

Polyclonal TLR4 Antibody

APG03001G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR4 . This antibody is tested and proven to work in the following applications:

Polyclonal TLR4 Antibody

AMM05417G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR4 . This antibody is tested and proven to work in the following applications:

TLR4 Conjugated Antibody

C35577 100ul
EUR 476.4

TLR4 Polyclonal Antibody

ABP57210-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TLR4 from Human, Mouse, Rat. This TLR4 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR4 Polyclonal Antibody

ABP57210-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TLR4 from Human, Mouse, Rat. This TLR4 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR4 Polyclonal Antibody

ABP57210-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of TLR4 from Human, Mouse, Rat. This TLR4 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR4 Polyclonal Antibody

ES8209-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against TLR4 from Human/Mouse/Rat. This antibody is tested and validated for IHC

TLR4 Polyclonal Antibody

ES8209-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against TLR4 from Human/Mouse/Rat. This antibody is tested and validated for IHC

TLR4 Polyclonal Antibody

EA180-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against TLR4 from Human/ Rat/ Mouse. This antibody is tested and validated for IHC

TLR4 Polyclonal Antibody

EA180-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against TLR4 from Human/ Rat/ Mouse. This antibody is tested and validated for IHC

Rat TLR4 ELISA Kit

ERT0076 96Tests
EUR 625.2

Goat TLR4 ELISA Kit

EGTT0076 96Tests
EUR 625.2

Mouse TLR4 ELISA Kit

EMT0076 96Tests
EUR 625.2

Sheep TLR4 ELISA Kit

EST0076 96Tests
EUR 625.2

Human TLR4 ELISA Kit

ELA-E0753h 96 Tests
EUR 988.8

TLR4 ELISA KIT|Human

EF001014 96 Tests
EUR 826.8

Human TLR4 ELISA Kit

EHT0076 96Tests
EUR 625.2

Mouse TLR4 ELISA Kit

STJ150331 1 kit
EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of TLR4 in Mouse serum, plasma and other biological fluids

Human TLR4 ELISA Kit

STJ150452 1 kit
EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of TLR4 in human serum, plasma and other biological fluids

Rabbit TLR4 ELISA Kit

ERTT0076 96Tests
EUR 625.2

Monkey TLR4 ELISA Kit

EMKT0076 96Tests
EUR 625.2

Bovine TLR4 ELISA Kit

EBT0076 96Tests
EUR 625.2

Canine TLR4 ELISA Kit

ECT0076 96Tests
EUR 625.2

Rat TLR4 shRNA Plasmid

20-abx985385
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Porcine TLR4 ELISA Kit

EPT0076 96Tests
EUR 625.2

Chicken TLR4 ELISA Kit

ECKT0076 96Tests
EUR 625.2

Anserini TLR4 ELISA Kit

EAT0076 96Tests
EUR 625.2

Antibody for Human TLR4

SPC-200D 0.1mg
EUR 386.4
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is unconjugated.

Antibody for Human TLR4

SPC-200D-A390 0.1mg
EUR 442.8
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to ATTO 390.

Antibody for Human TLR4

SPC-200D-A488 0.1mg
EUR 441.6
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to ATTO 488.

Antibody for Human TLR4

SPC-200D-A565 0.1mg
EUR 441.6
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to ATTO 565.

Antibody for Human TLR4

SPC-200D-A594 0.1mg
EUR 441.6
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to ATTO 594.

Antibody for Human TLR4

SPC-200D-A633 0.1mg
EUR 441.6
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to ATTO 633.

Antibody for Human TLR4

SPC-200D-A655 0.1mg
EUR 441.6
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to ATTO 655.

Antibody for Human TLR4

SPC-200D-A680 0.1mg
EUR 441.6
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to ATTO 680.

Antibody for Human TLR4

SPC-200D-A700 0.1mg
EUR 441.6
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to ATTO 700.

Antibody for Human TLR4

SPC-200D-ALP 0.1mg
EUR 434.4
Description: A polyclonal antibody for TLR4 from Human | Mouse. The antibody is produced in rabbit after immunization with Human Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. The Antibody is tested and validated for WB, IHC, ICC/IF, FCM, FACS assays with the following recommended dilutions: WB (1:500), IHC (1:50). This TLR4 antibody is conjugated to Alkaline Phosphatase.

TAK-242 dose dependency inhibit the expression of an increase in IL-6, IL-8, MMP-1 and VEGF in LPS-stimulated cells MH7A.

November 2023
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