Decreased Toll-like Receptor (TLR) 2 and 4 Expression in Spermatozoa in Couples with Unexplained Recurrent Spontaneous Abortion (URSA).

Decreased Toll-like Receptor (TLR) 2 and 4 Expression in Spermatozoa in Couples with Unexplained Recurrent Spontaneous Abortion (URSA).

Studies have shown that pulses like receptor (TLR) play several important roles in the process of reproduction such as ovulation, spermatogenesis, capacitation of sperm, fertilization, and pregnancy to the best of our knowledge, no study has evaluated the expression and role of these molecules and their decline in spermatozoa; accompanied with pregnancy complications such as recurrent spontaneous abortion (RSA). Therefore, this study investigated the changes in pulse like receptor 2 (TLR2) and pulses like receptor 4 (TLR4) expression in spermatozoa in men whose partner has described RSA.

Fifteen infertile couples and described fifteen couples with recurrent spontaneous abortion (URSA) were included in this study. TLR2 and TLR4 expression levels of untreated and lipopolysaccharide (LPS) or PAM3CYS in spermatozoa treated examined by flow cytometry. The results showed reduced expression of TLR4 in spermatozoa untreated and decreased levels of LPS or PAM3CYS in spermatozoa treated in URSA group compared with the control group. No significant differences were found in TLR2 expression untreated spermatozoa in the RSA and the control group. After treatment of spermatozoa with LPS, TLR2 expression was decreased in both groups.

After treatment of spermatozoa with PAM3CYS, TLR2 expression levels increased significantly in URSA group; while no significant differences were shown in the control group compared to the untreated spermatozoa. We have concluded that the decrease in the expression of TLR4 and TLR2 differ increased expression in response to ligands on the treatment of spermatozoa associated with Ursa.

Decreased Toll-like Receptor (TLR) 2 and 4 Expression in Spermatozoa in Couples with Unexplained Recurrent Spontaneous Abortion (URSA).
Decreased Toll-like Receptor (TLR) 2 and 4 Expression in Spermatozoa in Couples with Unexplained Recurrent Spontaneous Abortion (URSA).

Toll-like receptor (TLR) responds tributyltin chloride (TBT-Cl) of exposure at river puffer (Takifugu obscurus): Evidence for toxic injury function.

Tributyltin chloride (TBT-Cl) in the rest of the body of water has become a real problem for the aquatic ecosystem ecology. Toll-like receptor (TLR) is an ancient family of pattern recognition receptors that play a key role in detecting non-self antigens and activation of the immune system. In this study, we explored the effect of exposure to TBT-Cl in four expression of TLRs in the river puffer, Takifugu obscurus.

Fourth T. obscurus Toll-like receptor (To-TLRs) contained various types of domains like leucine-rich repeats (LRRs), leucine rich repeats, typical of the subfamily (LRR_TYP) and other specialized domains. To-TLRs mRNA transcripts expressed in all tissues, as well as To-TLR2 investigated with higher levels in the kidney, as well as To-TLR3 in the kidneys, while the To-TLR18 in the liver and To-TLR22 in the intestine. After the acute and chronic exposure of TBT-Cl, To-To-TLR2 and TLR3 mRNA transcripts were significantly down-regulated in the gills. However, To-To-TLR22 TLR18 and significantly up-regulated in the gills and liver.

In addition, histology and immunohistochemistry (IHC) results showed different degrees of injury of TBT-Cl in the liver and gills and implied the reorganization of the cytoplasm after the stress of TBT-Cl and immunoregulation function to the To-TLRs exposure to TBT-Cl. All results indicate that the To-TLRs might be involved in sensing and mediating innate immune response caused by TBT-Cl to maintain homeostasis detoxification.


BACKGROUND Myasthenia gravis (MG) is a progressive autoimmune disorder caused by the production of antibodies directed against acetylcholine receptors (AChRs), resulting in muscle weakness and fatigue. This study aimed to explore the effects and mechanism of grilled nux vomica (GNV) in experimental autoimmune myasthenia gravis (EAMG) mice.

TLR1 siRNA

20-abx936890
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  • 15 nmol
  • 30 nmol

TLR1 Peptide

3639P 0.05 mg
EUR 197.7
Description: (NT) TLR1 peptide

TLR1 Peptide

3641P 0.05 mg
EUR 197.7
Description: (IN) TLR1 peptide

TLR1 Antibody

ABD6179 100 ug
EUR 525.6

TLR1 antibody

20R-1578 100 ul
EUR 807.6
Description: Goat polyclonal TLR1 antibody

TLR1 Antibody

24361 100ul
EUR 479

TLR1 Antibody

24361-100ul 100ul
EUR 468

TLR1 Antibody

24362 100ul
EUR 479

TLR1 Antibody

24362-100ul 100ul
EUR 468

TLR1 Antibody

32117 100ul
EUR 439

TLR1 Antibody

32117-100ul 100ul
EUR 302.4

TLR1 Antibody

3639-002mg 0.02 mg
EUR 206.18
Description: TLR1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.

TLR1 Antibody

3639-01mg 0.1 mg
EUR 523.7
Description: TLR1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.

TLR1 Antibody

3641-002mg 0.02 mg
EUR 206.18
Description: TLR1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.

TLR1 Antibody

3641-01mg 0.1 mg
EUR 523.7
Description: TLR1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.

TLR1 Antibody

3446-100 each
EUR 405.6

TLR1 Antibody

1-CSB-PA953581
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  • 100ul
  • 50ul
Description: A polyclonal antibody against TLR1. Recognizes TLR1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50

TLR1 Antibody

E19-6179 100μg/100μl
EUR 225
Description: Available in various conjugation types.

TLR1 Antibody

CSB-PA023599KA01HU- each
EUR 402
Description: A polyclonal antibody against TLR1. Recognizes TLR1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

TLR1 Antibody

CSB-PA023599KA01HU-100ul 100ul
EUR 466.8
Description: A polyclonal antibody against TLR1. Recognizes TLR1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

TLR1 Antibody

1-CSB-PA023599LA01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR1. Recognizes TLR1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

TLR1 Antibody

DF6179 200ul
EUR 420

TLR1 Antibody

DF6179-100ul 100ul
EUR 280

TLR1 Antibody

DF6179-200ul 200ul
EUR 350

TLR1 Antibody

E90997 100ul
EUR 255
Description: Available in various conjugation types.

TLR1 Antibody

E308895 200ul
EUR 275
Description: Available in various conjugation types.

TLR1 antibody

70R-11831 100 ul
EUR 375
Description: Goat polyclonal TLR1 antibody

TLR1 Antibody

1-CSB-PA080182
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  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR1. Recognizes TLR1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1:200-500.ELISA:1/10000

TLR1 Antibody

GWB-3FBD9B 0.1 mg Ask for price

TLR1 Antibody

F44368-0.08ML 0.08 ml
EUR 140.25
Description: Higher animals establish host defense by orchestrating innate and adaptive immunity. This is mediated by professional antigen presenting cells, i.e. dendritic cells (DCs). DCs can incorporate pathogens, produce a variety of cytokines, maturate, and present pathogen-derived peptides to T cells, thereby inducing T cell activation and differentiation. These responses are triggered by microbial recognition through type I transmembrane proteins, Toll-like receptors (TLRs) on DCs. TLRs consist of ten members and each TLR is involved in recognizing a variety of microorganism-derived molecular structures. TLR ligands include cell wall components, proteins, nucleic acids, and synthetic chemical compounds, all of which can activate DCs as immune adjuvants. Each TLR can activate DCs in a similar, but distinct manner. For example, TLRs can be divided into subgroups according to their type I interferon (IFN) inducing ability. TLR2 cannot induce IFN-alpha or IFN-beta, but TLR4 can lead to IFN-beta production. Meanwhile, TLR3, TLR7, and TLR9 can induce both IFN-alpha and IFN-beta. Recent evidences suggest that cytoplamic adapters for TLRs are especially crucial for this functional heterogeneity.

TLR1 Antibody

F44368-0.4ML 0.4 ml
EUR 322.15
Description: Higher animals establish host defense by orchestrating innate and adaptive immunity. This is mediated by professional antigen presenting cells, i.e. dendritic cells (DCs). DCs can incorporate pathogens, produce a variety of cytokines, maturate, and present pathogen-derived peptides to T cells, thereby inducing T cell activation and differentiation. These responses are triggered by microbial recognition through type I transmembrane proteins, Toll-like receptors (TLRs) on DCs. TLRs consist of ten members and each TLR is involved in recognizing a variety of microorganism-derived molecular structures. TLR ligands include cell wall components, proteins, nucleic acids, and synthetic chemical compounds, all of which can activate DCs as immune adjuvants. Each TLR can activate DCs in a similar, but distinct manner. For example, TLRs can be divided into subgroups according to their type I interferon (IFN) inducing ability. TLR2 cannot induce IFN-alpha or IFN-beta, but TLR4 can lead to IFN-beta production. Meanwhile, TLR3, TLR7, and TLR9 can induce both IFN-alpha and IFN-beta. Recent evidences suggest that cytoplamic adapters for TLRs are especially crucial for this functional heterogeneity.

TLR1 Antibody

R31370 100 ug
EUR 356.15
Description: Toll-like receptor 1(TLR1), also called TIL or CD281 is a member of the Toll-like receptor family(TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

TLR1 Antibody

RQ6074 100 ug
EUR 356.15
Description: Toll-like receptor 1 (TLR1), also called TIL or CD281 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

TLR1 Antibody

RQ4250 100 ug
EUR 356.15
Description: Toll-like receptor 1 (TLR1), also called TIL or CD281 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Tlr1 (untagged) - Rat toll-like receptor 1 (Tlr1)

RN217213 10 µg Ask for price

TLR1 (untagged)-Human toll-like receptor 1 (TLR1)

SC118088 10 µg Ask for price

TLR1 Rabbit pAb

A0997-100ul 100 ul
EUR 369.6

TLR1 Rabbit pAb

A0997-200ul 200 ul
EUR 550.8

TLR1 Rabbit pAb

A0997-20ul 20 ul
EUR 219.6

TLR1 Rabbit pAb

A0997-50ul 50 ul
EUR 267.6

TLR1 Rabbit pAb

E2350147 100ul
EUR 225
Description: Available in various conjugation types.

TLR1 Rabbit pAb

E2350149 100ul
EUR 225
Description: Available in various conjugation types.

TLR1 (GFP-tagged) - Human toll-like receptor 1 (TLR1)

RG215218 10 µg Ask for price

Tlr1 (untagged) - Mouse toll-like receptor 1 (Tlr1), (10ug)

MC221701 10 µg Ask for price

TLR1 cloning plasmid

CSB-CL023599HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the TLR1 gene.

TLR1 Antibody (Biotin)

GWB-20D60F 0.25 ml Ask for price

TLR1 Blocking Peptide

DF6179-BP 1mg
EUR 234

TLR1 Polyclonal Antibody

ABP57211-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TLR1 from Human, Mouse, Rat. This TLR1 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR1 Polyclonal Antibody

ABP57211-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TLR1 from Human, Mouse, Rat. This TLR1 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR1 Polyclonal Antibody

ABP57211-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of TLR1 from Human, Mouse, Rat. This TLR1 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR1 Polyclonal Antibody

ABP57213-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TLR1 from Human, Mouse, Rat. This TLR1 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR1 Polyclonal Antibody

ABP57213-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TLR1 from Human, Mouse, Rat. This TLR1 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR1 Polyclonal Antibody

ABP57213-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of TLR1 from Human, Mouse, Rat. This TLR1 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

TLR1 Polyclonal Antibody

E20-53388 100ug
EUR 225
Description: Available in various conjugation types.

TLR1 Polyclonal Antibody

E20-53390 100ug
EUR 225
Description: Available in various conjugation types.

Polyclonal TLR1 Antibody

APR06374G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR1 . This antibody is tested and proven to work in the following applications:

Polyclonal TLR1 Antibody

APR06375G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR1 . This antibody is tested and proven to work in the following applications:

Polyclonal TLR1 Antibody

APG00001G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human TLR1 . This antibody is tested and proven to work in the following applications:

TLR1 Conjugated Antibody

C32117 100ul
EUR 476.4

TLR1 Polyclonal Antibody

E44H11011 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TLR1 Polyclonal Antibody

E44H11013 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TLR1 Polyclonal Antibody

E-AB-65724-120uL 120uL
EUR 320
Description: Unconjugated

TLR1 Polyclonal Antibody

E-AB-65724-200uL 200uL
EUR 530
Description: Unconjugated

TLR1 Polyclonal Antibody

E-AB-65724-60uL 60uL
EUR 200
Description: Unconjugated

TLR1 Polyclonal Antibody

E-AB-65724-each each Ask for price
Description: Unconjugated

Tlr1 (myc-DDK-tagged) - Rat toll-like receptor 1 (Tlr1)

RR217213 10 µg Ask for price

Tlr1 (GFP-tagged) - Mouse toll-like receptor 1 (Tlr1), (10ug)

MG226857 10 µg Ask for price

Tlr1 (Myc-DDK-tagged) - Mouse toll-like receptor 1 (Tlr1)

MR226857 10 µg Ask for price

TLR1 (Myc-DDK-tagged)-Human toll-like receptor 1 (TLR1)

RC215218 10 µg Ask for price

Human TLR1 ELISA Kit

EK5487 96 tests
EUR 599

Tlr1 (untagged) - Mouse toll-like receptor 1 (Tlr1), transcript variant 2

MC228948 10 µg Ask for price

Mouse TLR1 shRNA Plasmid

20-abx973135
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Human TLR1 shRNA Plasmid

20-abx954863
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  • Ask for price
  • 150 µg
  • 300 µg

TLR1 Antibody, HRP conjugated

1-CSB-PA023599LB01HU
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  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR1. Recognizes TLR1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

TLR1 Recombinant Protein (Rat)

RP233252 100 ug Ask for price

TLR1 Antibody, FITC conjugated

1-CSB-PA023599LC01HU
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR1. Recognizes TLR1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

OACD07798-1ML - TLR1 Antibody

OACD07798-1ML 1ml
EUR 639

OACD07799-1ML - TLR1 Antibody

OACD07799-1ML 1ml
EUR 639

OACD00840-1ML - TLR1 Antibody

OACD00840-1ML 1ml
EUR 659

OAAN00163-50UL - TLR1 Antibody

OAAN00163-50UL 50ul
EUR 149

OACA09489-50UG - TLR1 Antibody

OACA09489-50UG 50ug
EUR 179

TLR1 Recombinant Protein (Human)

RP044170 100 ug Ask for price

TLR1 Recombinant Protein (Mouse)

RP178949 100 ug Ask for price

TLR1 Rabbit Polyclonal Antibody

E12-364 100μg/100μl
EUR 225
Description: Available in various conjugation types.

TLR1 Rabbit Polyclonal Antibody

E12-366 100μg/100μl
EUR 225
Description: Available in various conjugation types.

TLR1 Antibody, Biotin conjugated

1-CSB-PA023599LD01HU
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  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against TLR1. Recognizes TLR1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

TLR1 Rabbit Polyclonal Antibody

EA183-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against TLR1 from Human/ Rat/ Mouse. This antibody is tested and validated for IHC

TLR1 Rabbit Polyclonal Antibody

EA183-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against TLR1 from Human/ Rat/ Mouse. This antibody is tested and validated for IHC

TLR1 Rabbit Polyclonal Antibody

ES8210-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against TLR1 from Human/Mouse/Rat. This antibody is tested and validated for IHC

TLR1 Rabbit Polyclonal Antibody

ES8210-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against TLR1 from Human/Mouse/Rat. This antibody is tested and validated for IHC

TLR1 Rabbit Polyclonal Antibody

ES8212-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against TLR1 from Human/Mouse/Rat. This antibody is tested and validated for IHC

TLR1 Rabbit Polyclonal Antibody

ES8212-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against TLR1 from Human/Mouse/Rat. This antibody is tested and validated for IHC

OACD07798-100UL - TLR1 Antibody

OACD07798-100UL 100ul
EUR 189

OACD07799-100UL - TLR1 Antibody

OACD07799-100UL 100ul
EUR 189

OACD00840-100UL - TLR1 Antibody

OACD00840-100UL 100ul
EUR 189

OAGA07661-100UL - TLR1 Antibody

OAGA07661-100UL 100ul
EUR 369

OAPB00357-100UG - TLR1 Antibody

OAPB00357-100UG 0.1mg
EUR 389

OAPB00358-100UG - TLR1 Antibody

OAPB00358-100UG 0.1mg
EUR 389

OASG07212-100UL - TLR1 Antibody

OASG07212-100UL 100ul
EUR 239

OASG07213-100UL - TLR1 Antibody

OASG07213-100UL 100ul
EUR 239

OAAJ06653-100UL - TLR1 Antibody

OAAJ06653-100UL 100uL
EUR 319

OAAN00163-100UL - TLR1 Antibody

OAAN00163-100UL 100ul
EUR 249

OAAN00163-200UL - TLR1 Antibody

OAAN00163-200UL 200ul
EUR 389

OACA09489-100UG - TLR1 Antibody

OACA09489-100UG 100ug
EUR 319

OAEG00989-100UG - TLR1 Antibody

OAEG00989-100UG 100ug
EUR 579

Rabbit Polyclonal TLR1 Antibody

TA306265 100 µg Ask for price

Rabbit Polyclonal TLR1 Antibody

TA306266 100 µg Ask for price

Rabbit Polyclonal TLR1 Antibody

TA336407 100 µg Ask for price

TLR1 Rabbit Polyclonal Antibody

E10G07010 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Polyclonal TLR1 Antibody (Internal)

APR02386G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR1 (Internal). This antibody is tested and proven to work in the following applications:

Lenti ORF clone of Tlr1 (mGFP-tagged) - Mouse toll-like receptor 1 (Tlr1)

MR226857L4 10 µg Ask for price

Tlr1 ORF Vector (Rat) (pORF)

ORF077752 1.0 ug DNA
EUR 607.2

CD281/TLR1 ELISA KIT|Human

EF007394 96 Tests
EUR 826.8

TLR1 ORF Vector (Human) (pORF)

ORF014724 1.0 ug DNA
EUR 424.8

Tlr1 ORF Vector (Mouse) (pORF)

ORF059651 1.0 ug DNA
EUR 607.2

Tlr1 (myc-DDK-tagged) - Mouse toll-like receptor 1 (Tlr1), transcript variant 2

MR231159 10 µg Ask for price

Human TLR1 PicoKine ELISA Kit

EK1129 96 wells
EUR 510
Description: For quantitative detection of human TLR1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human TLR1 knockout cell line

ABC-KH15472 1 vial Ask for price
Description: Human TLR1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Biotin anti-human CD281 (TLR1)

E16FHB281-100U 100 μg
EUR 1040
Description: Available in various conjugation types.

Human TLR1 knockdown cell line

ABC-KD15472 1 vial Ask for price
Description: Human TLR1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

TLR1 ELISA Kit (Human) (OKCD07880)

OKCD07880 96 Wells
EUR 1123.2
Description: Description of target: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.127ng/mL

TLR1 ELISA Kit (Mouse) (OKCD07881)

OKCD07881 96 Wells
EUR 981.6
Description: Description of target: Purified Rabbit Polyclonal Antibody (Pab);Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.108ng/mL

TLR1 ELISA Kit (Human) (OKAN05048)

OKAN05048 96 Wells
EUR 950.4
Description: Description of target: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.114 ng/mL

TLR1 ELISA Kit (Human) (OKBB00505)

OKBB00505 96 Wells
EUR 606
Description: Description of target: TLR1 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. TIR1 gene was mapped to 4p14 by fluorescence in situ hybridization. TLR1 recognizes pathogen-associated molecular pattern with a specificity for gram-positive bacteria. TLR1 has also been designated as CD281 (cluster of differentiation 281). TLR1 interacts with TLR2 to recognize the lipid configuration of the native mycobacterial lipoprotein as well as several triacylated lipopeptides.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Human Toll-like receptor (TLR1)

1-CSB-YP023599HU
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  • 100ug
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  • 1MG
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Description: Recombinant Human Toll-like receptor(TLR1),partial expressed in Yeast

Purified anti-human CD281 (TLR1)

E16FHU281-100U 100 μg
EUR 953.33
Description: Available in various conjugation types.

Genorise® Recombinant sheep TLR1

GR104083 5 µg
EUR 285

Genorise® Recombinant human TLR1

GR104195 5 µg
EUR 285

Lenti ORF clone of Tlr1 (Myc-DDK-tagged) - Mouse toll-like receptor 1 (Tlr1)

MR226857L3 10 µg Ask for price

Genorise® Recombinant equine TLR1

GR104008 5 µg
EUR 285

Genorise® Recombinant bovine TLR1

GR104058 5 µg
EUR 285

Genorise® Recombinant canine TLR1

GR104108 5 µg
EUR 285

Genorise® Recombinant Monkey TLR1

GR175017 5 mg
EUR 285

Genorise® Recombinant Donkey TLR1

GR176017 5 mg
EUR 285

Polyclonal TLR1 Antibody (aa400-450)

APR02824G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR1 (aa400-450). This antibody is tested and proven to work in the following applications:

Genorise® Recombinant porcine TLR1

GR104033 5 µg
EUR 285

Genorise® Recombinant chicken TLR1

GR104133 5 µg
EUR 285

Polyclonal TLR1 Antibody (N-Terminus)

APR02280G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR1 (N-Terminus). This antibody is tested and proven to work in the following applications:

TLR1 Over-expression Lysate Product

GWB-AC9FF3 0.1 mg Ask for price

h TLR1 inducible lentiviral particles

LVP743 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for expressing human target: h TLR1 (toll-like receptor 1), [alternative names: CD281; rsc786; TIL; TIL. LPRS5]. The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_003263. It also contains a RFP-Blasticidin dual selection marker.

TLR1 rabbit polyclonal antibody, Purified

AP07365PU-N 50 µg Ask for price

TLR1 rabbit polyclonal antibody, Purified

AP07788PU-N 50 µg Ask for price

OPCA03236-1MG - TLR1 Recombinant Protein

OPCA03236-1MG 1mg
EUR 3048

OPCD00528-10UG - TLR1 Recombinant Protein

OPCD00528-10UG 10ug
EUR 99

OPCD00528-50UG - TLR1 Recombinant Protein

OPCD00528-50UG 50ug
EUR 249

OPCA03236-20UG - TLR1 Recombinant Protein

OPCA03236-20UG 20ug
EUR 379

OPCD07486-10UG - TLR1 Recombinant Protein

OPCD07486-10UG 10ug
EUR 99

OPCD07486-50UG - TLR1 Recombinant Protein

OPCD07486-50UG 50ug
EUR 239

OPCD07487-10UG - TLR1 Recombinant Protein

OPCD07487-10UG 10ug
EUR 99

OPCD07487-50UG - TLR1 Recombinant Protein

OPCD07487-50UG 50ug
EUR 239

OPCD00528-200UG - TLR1 Recombinant Protein

OPCD00528-200UG 200ug
EUR 499

OPCA03236-100UG - TLR1 Recombinant Protein

OPCA03236-100UG 100ug
EUR 720

OPCD07486-200UG - TLR1 Recombinant Protein

OPCD07486-200UG 200ug
EUR 469

OPCD07487-200UG - TLR1 Recombinant Protein

OPCD07487-200UG 200ug
EUR 469

Nori® Duck TLR1 ELISA Kit

GR149047 96-well
EUR 461

Nori® Sheep TLR1 ELISA Kit

GR-116015 96-well
EUR 461

Nori® Mouse TLR1 ELISA Kit

GR117332 96-well
EUR 461

Nori® Bovine TLR1 ELISA Kit

GR112059 96-well
EUR 461

Nori® Rabbit TLR1 ELISA Kit

GR144356 96-well
EUR 461

Nori® Monkey TLR1 ELISA Kit

GR169041 96-well
EUR 461

Nori® Donkey TLR1 ELISA Kit

GR170041 96-well
EUR 461

Nori® Turkey TLR1 ELISA Kit

GR187047 96-well
EUR 461

Nori® Feline TLR1 ELISA Kit

GR188344 96-well
EUR 461

Nori® Ferret TLR1 ELISA Kit

GR201113 96-well
EUR 461

Nori® Salmon TLR1 ELISA Kit

GR202113 96-well
EUR 461

Nori® Chicken TLR1 ELISA Kit

GR114149 96-well
EUR 461

Nori® Hamster TLR1 ELISA Kit

GR172228 96-well
EUR 461

Nori® Porcine TLR1 ELISA Kit

GR113101 96-well
EUR 461

Toll-Like Receptor 1 (TLR1) (NT)

PC-579 Polyclonal Ask for price

Nori® Zebrafish TLR1 ELISA Kit

GR206113 96-well
EUR 461

Human TLR1-9 Agonist kit (10 ligands)

tlrl-kit1hw 1 kit
EUR 588

Mouse TLR1-9 Agonist kit (9 ligands)

tlrl-kit1mw 1 kit
EUR 560.7

Toll Like Receptor 1 (TLR1) Antibody

20-abx102056
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  • 100 ug
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  • 1 mg
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Toll Like Receptor 1 (TLR1) Antibody

20-abx102057
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  • 100 ug
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Toll Like Receptor 1 (TLR1) Antibody

20-abx130820
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  • 100 ug
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Toll Like Receptor 1 (TLR1) Antibody

20-abx131782
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  • 100 ug
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Toll Like Receptor 1 (TLR1) Antibody

20-abx211714
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Toll Like Receptor 1 (TLR1) Antibody

20-abx270116
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  • 100 tests
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  • 25 tests
  • 500 tests
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Toll Like Receptor 1 (TLR1) Antibody

20-abx174837
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  • 1 mg
  • 200 ug

Toll Like Receptor 1 (TLR1) Antibody

20-abx178627
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  • 1 mg
  • 200 ug

Toll Like Receptor 1 (TLR1) Antibody

20-abx326826
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  • 100 ug
  • 50 ug

MATERIALS AND METHODS Mice 97-116 peptides used to mediate the disease in the model EAMG in SPF female Lewis rats. The treatment group received grilled Nux Vomica (75 mg / kg, 150 mg / kg, and 225 mg / kg). The autoantibodies and inflammatory cytokine levels were measured by enzyme-linked immunosorbent assay (ELISA). RNA profiles done on the high dose group and rat models.

Sierra

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