Lipid-Mediated Insertion of Toll-Like Receptor (TLR) Ligands for Facile Immune Cell Engineering

Lipid-Mediated Insertion of Toll-Like Receptor (TLR) Ligands for Facile Immune Cell Engineering

cell-based immunotherapies has tremendous potential for treating various diseases, such as cancer or suppress the immune activating in autoimmune diseases. Most cell-based cancer immunotherapies in clinical adjuvant signaling through genetic engineering to improve the function of T cells, however, are genetically encoded signals have minimal control over the dosage and last for the life of cell lineages.

These properties make it difficult to balance the increase in therapeutic efficacy with reduced toxicity. Here, we demonstrate the potential ligand-coupled phospholipids as non-genetic system for the engineering of immune cells. This system provides a simple, controlled, non-genetic adjuvant delivery cells through insertion immune-mediated lipid in the plasma membrane.

Lipid-mediated insertion (called depoting) successfully sent Toll-like receptor (TLR) ligands to cell surface and intracellular immune cells are mixed. This ligand depoted into immune cells in a dose-controlled fashion and did not compete during the pairs multiplex loading. activation of immune cells can be enhanced by autocrine and paracrine mechanisms depending on the biology of TLR ligands tested.

Depoted functional ligand survive in the plasma membrane of up to 4 days in naive and activated T cells, increase their activation, proliferation, and cytokine secretion skewing. Our data suggest that adjuvant ligand depoted signaling persistent but non-permanent for immune cells that can minimize the intensity and duration of toxicity compared to permanent genetic delivery. Overall, the findings suggest the potential for lipid-mediated depoting as a universal cell engineering approaches with unique, complementary advantages for other cell engineering methods.

Lipid-Mediated Insertion of Toll-Like Receptor (TLR) Ligands for Facile Immune Cell Engineering
Lipid-Mediated Insertion of Toll-Like Receptor (TLR) Ligands for Facile Immune Cell Engineering

A Single and Multiple Ascending Dose Study of Toll-Like Receptor 7 (TLR 7) Agonist (RO7020531) in Chinese Healthy Volunteers.

TLR7 agonists modulate the activity of the immune broad spectrum and evaluated in the treatment of human diseases including cancer and chronic viral infections. RO7020531, a prodrug orally from agonist TLR7, is in clinical development as part of a regimen of curative against chronic hepatitis B. We report the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of RO7020531 in healthy volunteers of China following single and multiple dose ascending (SAD and MAD). PK and PD samples were evaluated from four cohorts of a three cohort SAD and MAD with 10 subjects each (8 active, 2 placebo). Safety and tolerability were monitored throughout the study. A total of 155 adverse events (AEs) were reported in 49 subjects. Fifty-one AE in 18 subjects were assessed as related to treatment. Most AEs were mild; nine subjects experienced moderate AE; no severe AEs.

In two cohorts of 150 mg given daily MAD (qod), 7 of the 20 subjects who experienced fever and asymptomatic temporarily halted because lymphopenia, completed 24-48 hours post-dose. PK of the active metabolite, RO7011785, increased linearly with doses of 40mg to 170mg. No accumulation following PK dose qod. PK profile consistent with observations in white subjects in the first study of human-in-global. single and multiple doses of RO7020531 resulted in dose-dependent increase in markers of response to TLR7 or above 100mg.

Rat Toll Like Receptor4 ELISA kit

E01A16898 96T
EUR 700
Description: ELISA

Rat Toll Like Receptor4 ELISA kit

E02T0069-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor4 ELISA kit

E02T0069-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor4 ELISA kit

E02T0069-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 5 ELISA

E01A17186 96T
EUR 700
Description: ELISA

Rat Toll Like Receptor 6 ELISA

E01A17187 96T
EUR 700
Description: ELISA

Rat Toll Like Receptor 9 ELISA

E01A16902 96T
EUR 700
Description: ELISA

Rat Toll Like Receptor 3 ELISA kit

E01A16895 96T
EUR 700
Description: ELISA

Rat Toll Like Receptor 7 ELISA kit

E01A16899 96T
EUR 700
Description: ELISA

Rat Toll Like Receptor 8 ELISA kit

E01A16900 96T
EUR 700
Description: ELISA

Rat Toll Like Receptor 3 ELISA kit

E02T0066-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 3 ELISA kit

E02T0066-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 3 ELISA kit

E02T0066-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 2 ELISA kit

E02T0068-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 2 ELISA kit

E02T0068-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 2 ELISA kit

E02T0068-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 7 ELISA kit

E02T0070-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 7 ELISA kit

E02T0070-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 7 ELISA kit

E02T0070-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 8 ELISA kit

E02T0071-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 8 ELISA kit

E02T0071-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 8 ELISA kit

E02T0071-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 9 ELISA kit

E02T0073-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 9 ELISA kit

E02T0073-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 9 ELISA kit

E02T0073-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 5 ELISA kit

E02T0755-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 5 ELISA kit

E02T0755-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 5 ELISA kit

E02T0755-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 6 ELISA kit

E02T0756-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 6 ELISA kit

E02T0756-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 6 ELISA kit

E02T0756-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll- like receptor 4 ELISA KIT

ELI-02590r 96 Tests
EUR 1063.2

Rat Toll Like Receptor 2 ELISA Kit

IRTTLR2KT each
EUR 718
Description: Rat Toll Like Receptor 2 ELISA Kit

Rat Toll Like Receptor 4 ELISA Kit

IRTTLR4KT each
EUR 718
Description: Rat Toll Like Receptor 4 ELISA Kit

Rat Toll Like Receptor 2 (TLR2) Protein

20-abx069359
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 4 (TLR4) Protein

20-abx069367
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 3 (TLR3) Protein

20-abx168805
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 5 (TLR5) Protein

20-abx168807
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  • 100 ug
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  • 1 mg
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Rat Toll Like Receptor 8 (TLR8) Protein

20-abx167615
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  • 100 ug
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  • 1 mg
  • 200 ug
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Rat Toll Like Receptor 9 (TLR9) Protein

20-abx167759
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  • 100 ug
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  • 1 mg
  • 200 ug
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Rat Toll Like Receptor 8 (TLR8) Protein

abx167615-1ml 1 ml
EUR 225

Rat Toll Like Receptor 9 (TLR9) Protein

abx167759-1ml 1 ml
EUR 237.5

Rat Toll Like Receptor 3 (TLR3) Protein

abx168805-1ml 1 ml
EUR 187.5

Rat Toll Like Receptor 5 (TLR5) Protein

abx168807-1ml 1 ml
EUR 225

Rat Toll Like Receptor 2 (TLR2) Protein

abx069359-25mg 25 mg
EUR 387.5

Rat Toll Like Receptor 2 (TLR2) Protein

abx069359-5mg 5 mg
EUR 212.5

Rat Toll Like Receptor 4 (TLR4) Protein

abx069367-25mg 25 mg
EUR 300

Rat Toll Like Receptor 4 (TLR4) Protein

abx069367-5mg 5 mg
EUR 187.5

Rat Toll Like Receptor 10 (TLR10) Protein

20-abx167568
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
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Rat Toll Like Receptor 10 (TLR10) Protein

abx167568-1ml 1 ml
EUR 212.5

Rat Toll Like Receptor 2 (TLR2) CLIA Kit

20-abx491848
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Toll Like Receptor 4 (TLR4) CLIA Kit

20-abx491986
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Toll Like Receptor 4 (TLR4) CLIA Kit

abx196320-100g 100 µg Ask for price

Rat Toll Like Receptor 4 (TLR4) CLIA Kit

abx196320-50g 50 µg
EUR 618.75

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

abx256053-96tests 96 tests
EUR 801.6

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

abx570235-96tests 96 tests
EUR 801.6

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

20-abx156174
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

20-abx156175
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Toll Like Receptor 6 (TLR6) ELISA Kit

abx353933-96tests 96 tests
EUR 943.2

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Ra 96T
EUR 454
Description: tissue homogenates, cell lysates or other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

DLR-TLR4-Ra 96T
EUR 454
Description: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

DLR-TLR4-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 4 (TLR4) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

DLR-TLR4-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 4 (TLR4) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

DL-TLR2-Ra 96T
EUR 432
Description: tissue homogenates, cell lysates or other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

DL-TLR4-Ra 96T
EUR 432
Description: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48860-48T 48T
EUR 370.02

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48860-5x96T 5x96T
EUR 2510.85

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

EKN48860-96T 96T
EUR 528.6

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

EKN48866-48T 48T
EUR 370.02

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

EKN48866-5x96T 5x96T
EUR 2510.85

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

EKN48866-96T 96T
EUR 528.6

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

EK16961 96Т
EUR 768

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

EK16967 96Т
EUR 768

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07749-48T 48T
EUR 542.78

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07749-5x96T 5x96T
EUR 3683.15

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

EKU07749-96T 96T
EUR 775.4

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

EKU07755-48T 48T
EUR 542.78

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

EKU07755-5x96T 5x96T
EUR 3683.15

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

EKU07755-96T 96T
EUR 775.4

Rat Toll Like Receptor 6(TLR6)ELISA Kit

QY-E10074 96T
EUR 433.2

Rat Toll Like Receptor 2(TLR2)ELISA Kit

QY-E10075 96T
EUR 433.2

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Ra-48T 48T
EUR 465.47
Description: tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Ra-48Tests 48 Tests
EUR 640.8

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Ra-96T 96T
EUR 664.97
Description: tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Ra-96Tests 96 Tests
EUR 890.4

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RDR-TLR4-Ra-48T 48T
EUR 465.47
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RDR-TLR4-Ra-48Tests 48 Tests
EUR 640.8

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RDR-TLR4-Ra-96T 96T
EUR 664.97
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RDR-TLR4-Ra-96Tests 96 Tests
EUR 890.4

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Ra-48T 48T
EUR 443.3
Description: tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Ra-48Tests 48 Tests
EUR 613.2

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Ra-96T 96T
EUR 633.3
Description: tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Ra-96Tests 96 Tests
EUR 850.8

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RD-TLR4-Ra-48T 48T
EUR 443.3
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RD-TLR4-Ra-48Tests 48 Tests
EUR 613.2

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RD-TLR4-Ra-96T 96T
EUR 633.3
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RD-TLR4-Ra-96Tests 96 Tests
EUR 850.8

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

4-SEA663Ra
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Toll Like Receptor 2 (TLR2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

SEA753Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 4 (TLR4) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

SEA753Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 4 (TLR4) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

SEA753Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 4 (TLR4) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

SEA753Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 4 (TLR4) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

4-SEA753Ra
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Toll Like Receptor 4 (TLR4) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Toll Like Receptor 7 (TLR7) ELISA Kit

SL1666Ra - Ask for price

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

abx256053-1096tests 10 × 96 tests Ask for price

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

abx256053-596tests 5 × 96 tests Ask for price

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

abx256341-1096tests 10 × 96 tests Ask for price

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

abx256341-596tests 5 × 96 tests Ask for price

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

abx156174-100g 100 µg
EUR 3212.5

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

abx156174-200g 200 µg
EUR 6075

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

abx156174-50g 50 µg
EUR 675

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

abx156175-100g 100 µg
EUR 3212.5

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

abx156175-200g 200 µg
EUR 6075

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

abx156175-50g 50 µg
EUR 675

Rat Toll Like Receptor 6 (TLR6) ELISA Kit

abx353933-1096tests 10 × 96 tests Ask for price

Rat Toll Like Receptor 6 (TLR6) ELISA Kit

abx353933-596tests 5 × 96 tests
EUR 587.5

LncRNA Profiler Complete qPCR Array Kit (cDNA synthesis kit, qPCR array and SYBR Green reagent) 20 profiles

RA910A-1 20 profiles
EUR 1329.6

Rat TLR2(Toll Like Receptor 2) ELISA Kit

ELK1977-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR2 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR2(Toll Like Receptor 2) ELISA Kit

ELK1977-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR2 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR4(Toll Like Receptor 4) ELISA Kit

ELK2106-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR4 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR4(Toll Like Receptor 4) ELISA Kit

ELK2106-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR4 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR3(Toll Like Receptor 3) ELISA Kit

ELK8389-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR3 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR3(Toll Like Receptor 3) ELISA Kit

ELK8389-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR3 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR1(Toll Like Receptor 1) ELISA Kit

ELK8390-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR1(Toll Like Receptor 1) ELISA Kit

ELK8390-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR7(Toll Like Receptor 7) ELISA Kit

ELK8392-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR7. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR7. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR7, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR7 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TLR7(Toll Like Receptor 7) ELISA Kit

ELK8392-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TLR7. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TLR7. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat TLR7, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TLR7 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat Toll Like Receptor 4, TLR4 GENLISA ELISA

KLR0080 1 x 96 wells
EUR 341

Rat Toll Like Receptor 3, TLR3 GENLISA ELISA

KLR0081 1 x 96 wells
EUR 341

Rat toll Like Receptor 1, TLR1 GENLISA ELISA

KLR2285 1 x 96 wells
EUR 341

Rat Toll Like Receptor 11, TLR11 GENLISA ELISA

KLR1558 1 x 96 wells
EUR 341

Rat Soluble toll like receptor 2 ELISA kit

E01A16595 96T
EUR 700
Description: ELISA

Rat Soluble toll like receptor 6 ELISA kit

E01A16596 96T
EUR 700
Description: ELISA

Rat Soluble toll like receptor 4 ELISA kit

E01A16778 96T
EUR 700
Description: ELISA

Rat Soluble toll like receptor 7 ELISA kit

E01A16779 96T
EUR 700
Description: ELISA

Rat Soluble toll like receptor 9 ELISA kit

E01A16780 96T
EUR 700
Description: ELISA

Rat Soluble toll like receptor 2 ELISA kit

E02S0293-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Soluble toll like receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 2 ELISA kit

E02S0293-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Soluble toll like receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 2 ELISA kit

E02S0293-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Soluble toll like receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 6 ELISA kit

E02S0294-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Soluble toll like receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 6 ELISA kit

E02S0294-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Soluble toll like receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 6 ELISA kit

E02S0294-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Soluble toll like receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Flu-like symptoms associated with interferon-α levels were higher. RO7020531 safe and well tolerated in healthy volunteers received China with multiple dose regimen of 150 mg qod.

Sierra

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