Lipid-Mediated Insertion of Toll-Like Receptor (TLR) Ligands for Facile Immune Cell Engineering

Lipid-Mediated Insertion of Toll-Like Receptor (TLR) Ligands for Facile Immune Cell Engineering

cell-based immunotherapies has tremendous potential for treating various diseases, such as cancer or suppress the immune activating in autoimmune diseases. Most cell-based cancer immunotherapies in clinical adjuvant signaling through genetic engineering to improve the function of T cells, however, are genetically encoded signals have minimal control over the dosage and last for the life of cell lineages.

These properties make it difficult to balance the increase in therapeutic efficacy with reduced toxicity. Here, we demonstrate the potential ligand-coupled phospholipids as non-genetic system for the engineering of immune cells. This system provides a simple, controlled, non-genetic adjuvant delivery cells through insertion immune-mediated lipid in the plasma membrane.

Lipid-mediated insertion (called depoting) successfully sent Toll-like receptor (TLR) ligands to cell surface and intracellular immune cells are mixed. This ligand depoted into immune cells in a dose-controlled fashion and did not compete during the pairs multiplex loading. activation of immune cells can be enhanced by autocrine and paracrine mechanisms depending on the biology of TLR ligands tested.

Depoted functional ligand survive in the plasma membrane of up to 4 days in naive and activated T cells, increase their activation, proliferation, and cytokine secretion skewing. Our data suggest that adjuvant ligand depoted signaling persistent but non-permanent for immune cells that can minimize the intensity and duration of toxicity compared to permanent genetic delivery. Overall, the findings suggest the potential for lipid-mediated depoting as a universal cell engineering approaches with unique, complementary advantages for other cell engineering methods.

Lipid-Mediated Insertion of Toll-Like Receptor (TLR) Ligands for Facile Immune Cell Engineering
Lipid-Mediated Insertion of Toll-Like Receptor (TLR) Ligands for Facile Immune Cell Engineering

A Single and Multiple Ascending Dose Study of Toll-Like Receptor 7 (TLR 7) Agonist (RO7020531) in Chinese Healthy Volunteers.

TLR7 agonists modulate the activity of the immune broad spectrum and evaluated in the treatment of human diseases including cancer and chronic viral infections. RO7020531, a prodrug orally from agonist TLR7, is in clinical development as part of a regimen of curative against chronic hepatitis B. We report the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of RO7020531 in healthy volunteers of China following single and multiple dose ascending (SAD and MAD). PK and PD samples were evaluated from four cohorts of a three cohort SAD and MAD with 10 subjects each (8 active, 2 placebo). Safety and tolerability were monitored throughout the study. A total of 155 adverse events (AEs) were reported in 49 subjects. Fifty-one AE in 18 subjects were assessed as related to treatment. Most AEs were mild; nine subjects experienced moderate AE; no severe AEs.

In two cohorts of 150 mg given daily MAD (qod), 7 of the 20 subjects who experienced fever and asymptomatic temporarily halted because lymphopenia, completed 24-48 hours post-dose. PK of the active metabolite, RO7011785, increased linearly with doses of 40mg to 170mg. No accumulation following PK dose qod. PK profile consistent with observations in white subjects in the first study of human-in-global. single and multiple doses of RO7020531 resulted in dose-dependent increase in markers of response to TLR7 or above 100mg.

Rat Toll Like Receptor 5 ELISA kit

E02T0755-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 5 ELISA kit

E02T0755-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 5 ELISA kit

E02T0755-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 6 ELISA kit

E02T0756-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 6 ELISA kit

E02T0756-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 6 ELISA kit

E02T0756-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 3 ELISA kit

E02T0066-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 3 ELISA kit

E02T0066-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 3 ELISA kit

E02T0066-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 2 ELISA kit

E02T0068-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 2 ELISA kit

E02T0068-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 2 ELISA kit

E02T0068-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 7 ELISA kit

E02T0070-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 7 ELISA kit

E02T0070-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 7 ELISA kit

E02T0070-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 8 ELISA kit

E02T0071-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 8 ELISA kit

E02T0071-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 8 ELISA kit

E02T0071-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 9 ELISA kit

E02T0073-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 9 ELISA kit

E02T0073-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll Like Receptor 9 ELISA kit

E02T0073-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Toll- like receptor 4 ELISA KIT

ELI-02590r 96 Tests
EUR 1063.2

Rat Toll Like Receptor 3 (TLR3) Protein

20-abx168805
  • EUR 644.40
  • EUR 292.80
  • EUR 1863.60
  • EUR 760.80
  • EUR 477.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 5 (TLR5) Protein

20-abx168807
  • EUR 828.00
  • EUR 343.20
  • EUR 2548.80
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 2 (TLR2) Protein

20-abx069359
  • EUR 794.40
  • EUR 326.40
  • EUR 2431.20
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 4 (TLR4) Protein

20-abx069367
  • EUR 627.60
  • EUR 292.80
  • EUR 1796.40
  • EUR 727.20
  • EUR 460.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 8 (TLR8) Protein

20-abx167615
  • EUR 828.00
  • EUR 343.20
  • EUR 2548.80
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 9 (TLR9) Protein

20-abx167759
  • EUR 878.40
  • EUR 343.20
  • EUR 2749.20
  • EUR 1045.20
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Toll Like Receptor 10 (TLR10) Protein

20-abx167568
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

LncRNA Profiler qPCR Array Kit (cDNA synthesis kit and qPCR array) 20 profiles

RA900A-1 20 profiles
EUR 1020

Rat Toll Like Receptor 2 (TLR2) CLIA Kit

20-abx491848
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Toll Like Receptor 4 (TLR4) CLIA Kit

20-abx491986
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

DLR-TLR2-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 2 (TLR2) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

DLR-TLR4-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 4 (TLR4) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

DLR-TLR4-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Toll Like Receptor 4 (TLR4) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

abx256053-96tests 96 tests
EUR 801.6

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

20-abx156174
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

20-abx156175
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

abx570235-96tests 96 tests
EUR 801.6

Rat Toll Like Receptor 6 (TLR6) ELISA Kit

abx353933-96tests 96 tests
EUR 943.2

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

SEA753Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 4 (TLR4) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

SEA753Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 4 (TLR4) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

SEA753Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 4 (TLR4) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

SEA753Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 4 (TLR4) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

4-SEA753Ra
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Toll Like Receptor 4 (TLR4) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

SEA663Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Toll Like Receptor 2 (TLR2) in Tissue homogenates, cell lysates and other biological fluids.

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

4-SEA663Ra
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Toll Like Receptor 2 (TLR2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Toll Like Receptor 6(TLR6)ELISA Kit

QY-E10074 96T
EUR 433.2

Rat Toll Like Receptor 2(TLR2)ELISA Kit

QY-E10075 96T
EUR 433.2

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Ra-48Tests 48 Tests
EUR 613.2

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RD-TLR2-Ra-96Tests 96 Tests
EUR 850.8

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RD-TLR4-Ra-48Tests 48 Tests
EUR 613.2

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RD-TLR4-Ra-96Tests 96 Tests
EUR 850.8

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Ra-48Tests 48 Tests
EUR 640.8

Rat Toll Like Receptor 2 (TLR2) ELISA Kit

RDR-TLR2-Ra-96Tests 96 Tests
EUR 890.4

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RDR-TLR4-Ra-48Tests 48 Tests
EUR 640.8

Rat Toll Like Receptor 4 (TLR4) ELISA Kit

RDR-TLR4-Ra-96Tests 96 Tests
EUR 890.4

Rat Toll Like Receptor 4 ELISA Kit (TLR4)

RK03989 96 Tests
EUR 625.2

Mouse LncRNA Profiler qPCR Array Kit (cDNA synthesis kit and qPCR array) 20 profiles

RA930A-1 20 profiles
EUR 1020

Rat Soluble toll like receptor 2 ELISA kit

E02S0293-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Soluble toll like receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 2 ELISA kit

E02S0293-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Soluble toll like receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 2 ELISA kit

E02S0293-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Soluble toll like receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 6 ELISA kit

E02S0294-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Soluble toll like receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 6 ELISA kit

E02S0294-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Soluble toll like receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Soluble toll like receptor 6 ELISA kit

E02S0294-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Soluble toll like receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Rat TLR2 (Toll Like Receptor 2)

ELK1977 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Toll Like Receptor 2 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Rat TLR4 (Toll Like Receptor 4)

ELK2106 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Toll Like Receptor 4 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Toll Like Receptor 3 (TLR3) Polyclonal Antibody (Rat)

4-PAB989Ra01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Toll Like Receptor 3 (TLR3)

Toll Like Receptor 5 (TLR5) Polyclonal Antibody (Rat)

4-PAB990Ra01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Toll Like Receptor 5 (TLR5)

Toll Like Receptor 8 (TLR8) Polyclonal Antibody (Rat)

4-PAB991Ra01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Toll Like Receptor 8 (TLR8)

Toll Like Receptor 2 (TLR2) Polyclonal Antibody (Rat)

4-PAA663Ra01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Toll Like Receptor 2 (TLR2)

Toll Like Receptor 9 (TLR9) Polyclonal Antibody (Rat)

4-PAA709Ra01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Toll Like Receptor 9 (TLR9)

Toll Like Receptor 4 (TLR4) Polyclonal Antibody (Rat)

4-PAA753Ra01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Toll Like Receptor 4 (TLR4)

Pig Toll Like Receptor4 ELISA kit

E07T0069-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Toll Like Receptor4 ELISA kit

E07T0069-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Toll Like Receptor4 ELISA kit

E07T0069-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Toll Like Receptor4 ELISA kit

E08T0069-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Toll Like Receptor4 ELISA kit

E08T0069-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Toll Like Receptor4 ELISA kit

E08T0069-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Toll Like Receptor 10 (TLR10) Polyclonal Antibody (Rat)

4-PAB992Ra01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Toll Like Receptor 10 (TLR10)

Goat Toll Like Receptor4 ELISA kit

E06T0069-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Toll Like Receptor4 ELISA kit

E06T0069-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Toll Like Receptor4 ELISA kit

E06T0069-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor4 ELISA kit

E01T0069-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor4 ELISA kit

E01T0069-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor4 ELISA kit

E01T0069-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor4 ELISA kit

E03T0069-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor4 ELISA kit

E03T0069-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor4 ELISA kit

E03T0069-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Toll Like Receptor4 ELISA kit

E09T0069-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Toll Like Receptor4 ELISA kit

E09T0069-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Toll Like Receptor4 ELISA kit

E09T0069-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Toll Like Receptor4 ELISA kit

E04T0069-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Toll Like Receptor4 ELISA kit

E04T0069-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Toll Like Receptor4 ELISA kit

E04T0069-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Toll Like Receptor4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Toll Like Receptor 3 (TLR3) Antibody

20-abx213506
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 7 (TLR7) Antibody

20-abx213599
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 7 (TLR7) Antibody

20-abx213600
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 1 (TLR1) Antibody

20-abx211714
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212302
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212303
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212686
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 2 (TLR2) Antibody

20-abx212687
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 8 (TLR8) Antibody

20-abx212688
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 8 (TLR8) Antibody

20-abx212942
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 3 (TLR3) Antibody

20-abx213363
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Toll Like Receptor 1 (TLR1) Antibody

20-abx102056
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 1 (TLR1) Antibody

20-abx102057
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102058
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102059
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102060
  • EUR 376.80
  • EUR 944.40
  • EUR 493.20
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102061
  • EUR 376.80
  • EUR 944.40
  • EUR 493.20
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx102062
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 3 (TLR3) Antibody

20-abx102063
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 3 (TLR3) Antibody

20-abx102064
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 3 (TLR3) Antibody

20-abx102065
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 3 (TLR3) Antibody

20-abx102066
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 4 (TLR4) Antibody

20-abx102067
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 4 (TLR4) Antibody

20-abx102068
  • EUR 360.00
  • EUR 159.60
  • EUR 927.60
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 4 (TLR4) Antibody

20-abx102069
  • EUR 360.00
  • EUR 159.60
  • EUR 961.20
  • EUR 510.00
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 5 (TLR5) Antibody

20-abx102070
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 5 (TLR5) Antibody

20-abx102071
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 5 (TLR5) Antibody

20-abx102072
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 5 (TLR5) Antibody

20-abx102073
  • EUR 393.60
  • EUR 978.00
  • EUR 510.00
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Toll Like Receptor 6 (TLR6) Antibody

20-abx102074
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 6 (TLR6) Antibody

20-abx102075
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 7 (TLR7) Antibody

20-abx102076
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 8 (TLR8) Antibody

20-abx102077
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx326823
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Toll Like Receptor 6 (TLR6) Antibody

20-abx326824
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Toll Like Receptor 8 (TLR8) Antibody

20-abx326825
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Toll Like Receptor 1 (TLR1) Antibody

20-abx326826
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Toll Like Receptor 1 (TLR1) Antibody

20-abx174837
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx174839
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Toll Like Receptor 3 (TLR3) Antibody

20-abx174840
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Toll Like Receptor 4 (TLR4) Antibody

20-abx174841
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Toll Like Receptor 4 (TLR4) Antibody

20-abx174842
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Toll Like Receptor 6 (TLR6) Antibody

20-abx174843
  • EUR 944.40
  • EUR 493.20
  • 1 mg
  • 200 ug

Toll Like Receptor 7 (TLR7) Antibody

20-abx174844
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Toll Like Receptor 8 (TLR8) Antibody

20-abx174845
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Toll Like Receptor 9 (TLR9) Antibody

20-abx174846
  • EUR 944.40
  • EUR 493.20
  • 1 mg
  • 200 ug

Toll Like Receptor 1 (TLR1) Antibody

20-abx178627
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Toll Like Receptor 2 (TLR2) Antibody

20-abx178628
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Toll Like Receptor 4 (TLR4) Antibody

20-abx178629
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Flu-like symptoms associated with interferon-α levels were higher. RO7020531 safe and well tolerated in healthy volunteers received China with multiple dose regimen of 150 mg qod.

Sierra

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