innate immunity is driven by pattern recognition receptor (PRR) protect the host from the pathogen. aquatic animals such as fish where adaptive immunity is less developed majorly rely on their innate immunity is affected by PRRS like pulses like receptors (TLRs) and NOD like receptors (NLR). However, recent developments to improve the immunity of fish through the TLR / NLR signals may be affected by a poor understanding of the mechanistic and structural features.

This review discusses the structure of fish TLRs / NLRs and interaction with pathogen associated molecular patterns (PAMPs) and downstream signaling molecules. Over the past decade, significant progress has been made in studying the structure of TLRs / NLRs in higher eukaryotes;

However, structural studies on innate immune receptors damaged fish. Several new TLR genes identified in fish that are not present in higher eukaryotes, but this function is still poorly understood. Unlike the basic advances achieved in developing antagonists / agonists to modulate the innate human immunity, analog study on fish almost less because of structural deficiencies. This underlies the importance of exploring the structural and mechanistic details fish TLRs / NLRs at the level of atoms and molecules. This review described the basic mechanistic and structural fish and NLR TLR activation.

Targeting Toll like Receptors in Cancer: Role of TLR Natural and Synthetic Modulators

Background: Toll like receptor (TLR) is a transmembrane receptor belonging to the group area of ​​pattern recognition receptor classes (PRR), is involved in the recognition of Pathogen Associated Molecular Patterns (PAMPs) and thereby drive the immune response. In addition to these exogenous PAMPs, many PAMPs endogenous ligand also for various TLRs to activate TLR dependent immune response, then leads to the onset of the inflammatory response. Prolonged activation of TLRs by PAMPs endogenous insult leads to chronic inflammation in the body and which in turn alter the proliferative pattern of cells, which eventually lead to cancer development.

Objective: Review aims to present to provide a detailed outline of the various TLRs differential role in cancer and the possibility of their use as a therapeutic target.

Methods: Data were collected from PubMed / ScienceDirect / Web of Science database and sorted; Recent literature on TLRs established in the review.

Results: Among the different TLRs, few of the reported anti-neoplastic, that control cell growth and multiplication in response to endogenous signals. In contrast, many studies have reported pro-carcinogenic potential of TLRs. Therefore, TLRs have emerged as potential targets for the prevention and treatment of various cancers. Some molecules such as monoclonal antibodies, small molecule inhibitors and natural products have shown promising anticancer potential by effectively modulating TLR signaling.
Conclusion: Toll like receptor plays an important role in the carcinogenesis process, then the targeting TLR is a promising approach for cancer prevention.

We evaluated gene expression patterns TLRs (TLR1 to TLR9) in T47D and MDA-MB-468 cells using real-time qPCR analysis. Intracellular expression of TLR9 protein was studied by flow cytometry. Effect of CpG ODN on cell viability was tested by using MTT assay.

Human Toll Like Receptor 2 ELISA kit
E01T0068-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 2 ELISA kit
E01T0068-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 2 ELISA kit
E01T0068-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 7 ELISA kit
E01T0070-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 7 ELISA kit
E01T0070-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 7 ELISA kit
E01T0070-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 8 ELISA kit
E01T0071-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 8 ELISA kit
E01T0071-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 8 ELISA kit
E01T0071-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 9 ELISA kit
E01T0073-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 9 ELISA kit
E01T0073-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 9 ELISA kit
E01T0073-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 5 ELISA kit
E01T0755-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 5 ELISA kit
E01T0755-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 5 ELISA kit
E01T0755-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 6 ELISA kit
E01T0756-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 6 ELISA kit
E01T0756-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll Like Receptor 6 ELISA kit
E01T0756-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Toll- like receptor 1 ELISA Kit
ELA-E1988h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 8 ELISA Kit
ELA-E1991h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 10 ELISA Kit
ELA-E1992h	Lifescience Market	96 Tests	EUR 988.8

Human Toll Like Receptor 1 (TLR1) Protein
20-abx069356	Abbexa	EUR 627.60 EUR 292.80 EUR 1796.40 EUR 727.20 EUR 460.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 1 (TLR1) Protein
20-abx069357	Abbexa	EUR 627.60 EUR 292.80 EUR 1796.40 EUR 727.20 EUR 460.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 2 (TLR2) Protein
20-abx069358	Abbexa	EUR 627.60 EUR 292.80 EUR 1796.40 EUR 727.20 EUR 460.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 2 (TLR2) Protein
20-abx069360	Abbexa	EUR 627.60 EUR 292.80 EUR 1796.40 EUR 727.20 EUR 460.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 3 (TLR3) Protein
20-abx069361	Abbexa	EUR 594.00 EUR 292.80 EUR 1696.80 EUR 693.60 EUR 427.20	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 4 (TLR4) Protein
20-abx069365	Abbexa	EUR 710.40 EUR 309.60 EUR 2131.20 EUR 844.80 EUR 526.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 5 (TLR5) Protein
20-abx069368	Abbexa	EUR 510.00 EUR 276.00 EUR 1378.80 EUR 594.00 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 5 (TLR5) Protein
20-abx069369	Abbexa	EUR 510.00 EUR 276.00 EUR 1378.80 EUR 594.00 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 5 (TLR5) Protein
20-abx069370	Abbexa	EUR 510.00 EUR 276.00 EUR 1378.80 EUR 594.00 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 6 (TLR6) Protein
20-abx069371	Abbexa	EUR 828.00 EUR 343.20 EUR 2548.80 EUR 978.00 EUR 594.00	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 7 (TLR7) Protein
20-abx069373	Abbexa	EUR 828.00 EUR 343.20 EUR 2548.80 EUR 978.00 EUR 594.00	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 8 (TLR8) Protein
20-abx069374	Abbexa	EUR 693.60 EUR 309.60 EUR 2064.00 EUR 828.00 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 4 (TLR4) Protein
20-abx168661	Abbexa	EUR 693.60 EUR 309.60 EUR 2047.20 EUR 811.20 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 9 (TLR9) Protein
20-abx166661	Abbexa	EUR 794.40 EUR 326.40 EUR 2448.00 EUR 944.40 EUR 577.20	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 10 (TLR10) Protein
20-abx168288	Abbexa	EUR 878.40 EUR 343.20 EUR 2715.60 EUR 1045.20 EUR 627.60	100 ug 10 ug 1 mg 200 ug 50 ug

Human Toll Like Receptor 9 (TLR9) CLIA Kit
20-abx190355	Abbexa	EUR 9493.20 EUR 5058.00 EUR 1167.60	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 7 (TLR7) CLIA Kit
20-abx493284	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 1 (TLR1) CLIA Kit
20-abx493338	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 3 (TLR3) CLIA Kit
20-abx493340	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 5 (TLR5) CLIA Kit
20-abx493341	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 8 (TLR8) CLIA Kit
20-abx493342	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 2 (TLR2) CLIA Kit
20-abx491846	Abbexa	EUR 8853.60 EUR 4719.60 EUR 1093.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 6 (TLR6) CLIA Kit
20-abx491878	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 4 (TLR4) CLIA Kit
20-abx491985	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 9 (TLR9)CLIA Kit
SCA709Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 6777.36
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Toll Like Receptor 9 (TLR9) in serum, plasma, tissue homogenates and other biological fluids.

Human Toll Like Receptor 9 (TLR9)CLIA Kit
SCA709Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 663.31
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Toll Like Receptor 9 (TLR9) in serum, plasma, tissue homogenates and other biological fluids.

Human Toll Like Receptor 9 (TLR9)CLIA Kit
SCA709Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 896.16
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Toll Like Receptor 9 (TLR9) in serum, plasma, tissue homogenates and other biological fluids.

Human Toll Like Receptor 9 (TLR9)CLIA Kit
SCA709Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 3672.72
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Toll Like Receptor 9 (TLR9) in serum, plasma, tissue homogenates and other biological fluids.

Human Toll Like Receptor 9 (TLR9) CLIA Kit
4-SCA709Hu	Cloud-Clone	EUR 6837.60 EUR 3673.20 EUR 896.40	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Toll Like Receptor 9 (TLR9)Serum, plasma, tissue homogenates and other biological fluids

Human Toll Like Receptor 1 (TLR1) ELISA Kit
abx257473-96tests	Abbexa	96 tests	EUR 764.4

Human Toll Like Receptor 7 (TLR7) ELISA Kit
abx251340-96tests	Abbexa	96 tests	EUR 801.6

Human Toll Like Receptor 5 (TLR5) ELISA Kit
abx251361-96tests	Abbexa	96 tests	EUR 895.2

Human Toll Like Receptor 3 (TLR3) ELISA Kit
abx252402-96tests	Abbexa	96 tests	EUR 895.2

Human Toll Like Receptor 4 (TLR4) ELISA Kit
abx250274-96tests	Abbexa	96 tests	EUR 904.8

Human Toll Like Receptor 10 (TLR10) CLIA Kit
20-abx493343	Abbexa	EUR 9567.60 EUR 5095.20 EUR 1177.20	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 1 (TLR1) ELISA Kit
abx358465-96tests	Abbexa	96 tests	EUR 943.2

Human Toll Like Receptor 2 (TLR2) ELISA Kit
abx572097-96tests	Abbexa	96 tests	EUR 801.6

Human Toll Like Receptor 5 (TLR5) ELISA Kit
abx572247-96tests	Abbexa	96 tests	EUR 801.6

Human Toll Like Receptor 8 (TLR8) ELISA Kit
abx572248-96tests	Abbexa	96 tests	EUR 801.6

Human Toll Like Receptor 6 (TLR6) ELISA Kit
abx572429-96tests	Abbexa	96 tests	EUR 801.6

Human Toll Like Receptor 9 (TLR9) ELISA Kit
abx570187-96tests	Abbexa	96 tests	EUR 801.6

Human Toll Like Receptor 3 (TLR3) ELISA Kit
abx576351-96tests	Abbexa	96 tests	EUR 801.6

Human Toll Like Receptor 4 (TLR4) ELISA Kit
abx570146-96tests	Abbexa	96 tests	EUR 904.8

Human Toll Like Receptor 1 (TLR1) ELISA Kit
abx570435-96tests	Abbexa	96 tests	EUR 943.2

Human Toll Like Receptor 1 (TLR1) ELISA Kit
DLR-TLR1-Hu-48T	DL Develop	48T	EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 1 (TLR1) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Toll Like Receptor 1 (TLR1) ELISA Kit
DLR-TLR1-Hu-96T	DL Develop	96T	EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 1 (TLR1) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Toll Like Receptor 2 (TLR2) ELISA Kit
DLR-TLR2-Hu-48T	DL Develop	48T	EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 2 (TLR2) in samples from serum, plasma, tissue homogenates, cell lysates, saliva, cell culture supernates or other biological fluids.

Human Toll Like Receptor 2 (TLR2) ELISA Kit
DLR-TLR2-Hu-96T	DL Develop	96T	EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 2 (TLR2) in samples from serum, plasma, tissue homogenates, cell lysates, saliva, cell culture supernates or other biological fluids.

Human Toll Like Receptor 3 (TLR3) ELISA Kit
DLR-TLR3-Hu-48T	DL Develop	48T	EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 3 (TLR3) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Toll Like Receptor 3 (TLR3) ELISA Kit
DLR-TLR3-Hu-96T	DL Develop	96T	EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 3 (TLR3) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Toll Like Receptor 4 (TLR4) ELISA Kit
DLR-TLR4-Hu-48T	DL Develop	48T	EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 4 (TLR4) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 4 (TLR4) ELISA Kit
DLR-TLR4-Hu-96T	DL Develop	96T	EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 4 (TLR4) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 5 (TLR5) ELISA Kit
DLR-TLR5-Hu-48T	DL Develop	48T	EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 5 (TLR5) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 5 (TLR5) ELISA Kit
DLR-TLR5-Hu-96T	DL Develop	96T	EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 5 (TLR5) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 6 (TLR6) ELISA Kit
DLR-TLR6-Hu-48T	DL Develop	48T	EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 6 (TLR6) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 6 (TLR6) ELISA Kit
DLR-TLR6-Hu-96T	DL Develop	96T	EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 6 (TLR6) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 7 (TLR7) ELISA Kit
DLR-TLR7-Hu-48T	DL Develop	48T	EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 7 (TLR7) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 7 (TLR7) ELISA Kit
DLR-TLR7-Hu-96T	DL Develop	96T	EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 7 (TLR7) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 8 (TLR8) ELISA Kit
DLR-TLR8-Hu-48T	DL Develop	48T	EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 8 (TLR8) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Toll Like Receptor 8 (TLR8) ELISA Kit
DLR-TLR8-Hu-96T	DL Develop	96T	EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 8 (TLR8) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Toll Like Receptor 9 (TLR9) ELISA Kit
DLR-TLR9-Hu-48T	DL Develop	48T	EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 9 (TLR9) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 9 (TLR9) ELISA Kit
DLR-TLR9-Hu-96T	DL Develop	96T	EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Toll Like Receptor 9 (TLR9) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Toll Like Receptor 1 (TLR1) ELISA Kit
20-abx153340	Abbexa	EUR 8534.40 EUR 4550.40 EUR 1054.80	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 2 (TLR2) ELISA Kit
20-abx153342	Abbexa	EUR 6768.00 EUR 3610.80 EUR 848.40	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 3 (TLR3) ELISA Kit
20-abx153343	Abbexa	EUR 8534.40 EUR 4550.40 EUR 1054.80	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 4 (TLR4) ELISA Kit
20-abx153344	Abbexa	EUR 7970.40 EUR 4250.40 EUR 990.00	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 5 (TLR5) ELISA Kit
20-abx153345	Abbexa	EUR 8534.40 EUR 4550.40 EUR 1054.80	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 6 (TLR6) ELISA Kit
20-abx153346	Abbexa	EUR 7970.40 EUR 4250.40 EUR 990.00	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 7 (TLR7) ELISA Kit
20-abx153347	Abbexa	EUR 8534.40 EUR 4550.40 EUR 1054.80	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 8 (TLR8) ELISA Kit
20-abx153348	Abbexa	EUR 8534.40 EUR 4550.40 EUR 1054.80	10 × 96 tests 5 × 96 tests 96 tests

Human Toll Like Receptor 9 (TLR9) ELISA Kit
20-abx153349	Abbexa	EUR 7970.40 EUR 4250.40 EUR 990.00	10 × 96 tests 5 × 96 tests 96 tests

Human Toll- like receptor 2, TLR2 ELISA KIT
ELI-02326h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 6, TLR6 ELISA KIT
ELI-02377h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 9, TLR9 ELISA KIT
ELI-02465h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 4, TLR4 ELISA KIT
ELI-02588h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 7, TLR7 ELISA KIT
ELI-06263h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 1, TLR1 ELISA KIT
ELI-06396h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 3, TLR3 ELISA KIT
ELI-06397h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 5, TLR5 ELISA KIT
ELI-06400h	Lifescience Market	96 Tests	EUR 988.8

Human Toll- like receptor 8, TLR8 ELISA KIT
ELI-06403h	Lifescience Market	96 Tests	EUR 988.8

Human Toll Like Receptor 1 (TLR1) ELISA Kit
SEB988Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 1 (TLR1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 1 (TLR1) ELISA Kit
SEB988Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 1 (TLR1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 1 (TLR1) ELISA Kit
SEB988Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 1 (TLR1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 1 (TLR1) ELISA Kit
SEB988Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 1 (TLR1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 1 (TLR1) ELISA Kit
4-SEB988Hu	Cloud-Clone	EUR 5463.60 EUR 2886.00 EUR 735.60	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Toll Like Receptor 1 (TLR1) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Toll Like Receptor 3 (TLR3) ELISA Kit
SEB989Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 3 (TLR3) in tissue homogenates, cell lysates and other biological fluids.

Human Toll Like Receptor 3 (TLR3) ELISA Kit
SEB989Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 3 (TLR3) in tissue homogenates, cell lysates and other biological fluids.

Human Toll Like Receptor 3 (TLR3) ELISA Kit
SEB989Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 3 (TLR3) in tissue homogenates, cell lysates and other biological fluids.

Human Toll Like Receptor 3 (TLR3) ELISA Kit
SEB989Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 3 (TLR3) in tissue homogenates, cell lysates and other biological fluids.

Human Toll Like Receptor 3 (TLR3) ELISA Kit
4-SEB989Hu	Cloud-Clone	EUR 5463.60 EUR 2886.00 EUR 735.60	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Toll Like Receptor 3 (TLR3) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Toll Like Receptor 5 (TLR5) ELISA Kit
SEB990Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 5 (TLR5) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 5 (TLR5) ELISA Kit
SEB990Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 5 (TLR5) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 5 (TLR5) ELISA Kit
SEB990Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 5 (TLR5) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 5 (TLR5) ELISA Kit
SEB990Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 5 (TLR5) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 5 (TLR5) ELISA Kit
4-SEB990Hu	Cloud-Clone	EUR 5463.60 EUR 2886.00 EUR 735.60	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Toll Like Receptor 5 (TLR5) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Toll Like Receptor 8 (TLR8) ELISA Kit
SEB991Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 8 (TLR8) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 8 (TLR8) ELISA Kit
SEB991Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 8 (TLR8) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 8 (TLR8) ELISA Kit
SEB991Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 8 (TLR8) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 8 (TLR8) ELISA Kit
SEB991Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 8 (TLR8) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 8 (TLR8) ELISA Kit
4-SEB991Hu	Cloud-Clone	EUR 5463.60 EUR 2886.00 EUR 735.60	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Toll Like Receptor 8 (TLR8) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Toll Like Receptor 7 (TLR7) ELISA Kit
SEB950Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 7 (TLR7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 7 (TLR7) ELISA Kit
SEB950Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 7 (TLR7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 7 (TLR7) ELISA Kit
SEB950Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 7 (TLR7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 7 (TLR7) ELISA Kit
SEB950Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Toll Like Receptor 7 (TLR7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Toll Like Receptor 7 (TLR7) ELISA Kit
4-SEB950Hu	Cloud-Clone	EUR 5463.60 EUR 2886.00 EUR 735.60	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Toll Like Receptor 7 (TLR7) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Toll Like Receptor 1 ELISA Kit (TLR1)
RK02395	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 2 ELISA Kit (TLR2)
RK02397	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 3 ELISA Kit (TLR3)
RK02398	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 4 ELISA Kit (TLR4)
RK02399	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 5 ELISA Kit (TLR5)
RK02400	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 6 ELISA Kit (TLR6)
RK02401	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 7 ELISA Kit (TLR7)
RK02402	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 8 ELISA Kit (TLR8)
RK02403	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 9 ELISA Kit (TLR9)
RK02404	Abclonal	96 Tests	EUR 625.2

Human Toll Like Receptor 1 (TLR1) ELISA Kit
RDR-TLR1-Hu-48Tests	Reddot Biotech	48 Tests	EUR 626.4

Human Toll Like Receptor 1 (TLR1) ELISA Kit
RDR-TLR1-Hu-96Tests	Reddot Biotech	96 Tests	EUR 868.8

Human Toll Like Receptor 2 (TLR2) ELISA Kit
RDR-TLR2-Hu-48Tests	Reddot Biotech	48 Tests	EUR 600

Human Toll Like Receptor 2 (TLR2) ELISA Kit
RDR-TLR2-Hu-96Tests	Reddot Biotech	96 Tests	EUR 830.4

Human Toll Like Receptor 3 (TLR3) ELISA Kit
RDR-TLR3-Hu-48Tests	Reddot Biotech	48 Tests	EUR 626.4

Human Toll Like Receptor 3 (TLR3) ELISA Kit
RDR-TLR3-Hu-96Tests	Reddot Biotech	96 Tests	EUR 868.8

Human Toll Like Receptor 4 (TLR4) ELISA Kit
RDR-TLR4-Hu-48Tests	Reddot Biotech	48 Tests	EUR 600

Human Toll Like Receptor 4 (TLR4) ELISA Kit
RDR-TLR4-Hu-96Tests	Reddot Biotech	96 Tests	EUR 830.4

Human Toll Like Receptor 5 (TLR5) ELISA Kit
RDR-TLR5-Hu-48Tests	Reddot Biotech	48 Tests	EUR 626.4

Human Toll Like Receptor 5 (TLR5) ELISA Kit
RDR-TLR5-Hu-96Tests	Reddot Biotech	96 Tests	EUR 868.8

Human Toll Like Receptor 6 (TLR6) ELISA Kit
RDR-TLR6-Hu-48Tests	Reddot Biotech	48 Tests	EUR 600

Human Toll Like Receptor 6 (TLR6) ELISA Kit
RDR-TLR6-Hu-96Tests	Reddot Biotech	96 Tests	EUR 830.4

Human Toll Like Receptor 7 (TLR7) ELISA Kit
RDR-TLR7-Hu-48Tests	Reddot Biotech	48 Tests	EUR 626.4

Human Toll Like Receptor 7 (TLR7) ELISA Kit
RDR-TLR7-Hu-96Tests	Reddot Biotech	96 Tests	EUR 868.8

Human Toll Like Receptor 8 (TLR8) ELISA Kit
RDR-TLR8-Hu-48Tests	Reddot Biotech	48 Tests	EUR 626.4

Human Toll Like Receptor 8 (TLR8) ELISA Kit
RDR-TLR8-Hu-96Tests	Reddot Biotech	96 Tests	EUR 868.8

Human Toll Like Receptor 9 (TLR9) ELISA Kit
RDR-TLR9-Hu-48Tests	Reddot Biotech	48 Tests	EUR 600

Human Toll Like Receptor 9 (TLR9) ELISA Kit
RDR-TLR9-Hu-96Tests	Reddot Biotech	96 Tests	EUR 830.4

Human Toll Like Receptor 1 (TLR1) ELISA Kit
RD-TLR1-Hu-48Tests	Reddot Biotech	48 Tests	EUR 600

Human Toll Like Receptor 1 (TLR1) ELISA Kit
RD-TLR1-Hu-96Tests	Reddot Biotech	96 Tests	EUR 830.4

Human Toll Like Receptor 2 (TLR2) ELISA Kit
RD-TLR2-Hu-48Tests	Reddot Biotech	48 Tests	EUR 573.6

Human Toll Like Receptor 2 (TLR2) ELISA Kit
RD-TLR2-Hu-96Tests	Reddot Biotech	96 Tests	EUR 794.4

Human Toll Like Receptor 3 (TLR3) ELISA Kit
RD-TLR3-Hu-48Tests	Reddot Biotech	48 Tests	EUR 600

Human Toll Like Receptor 3 (TLR3) ELISA Kit
RD-TLR3-Hu-96Tests	Reddot Biotech	96 Tests	EUR 830.4

Human Toll Like Receptor 4 (TLR4) ELISA Kit
RD-TLR4-Hu-48Tests	Reddot Biotech	48 Tests	EUR 573.6

Human Toll Like Receptor 4 (TLR4) ELISA Kit
RD-TLR4-Hu-96Tests	Reddot Biotech	96 Tests	EUR 794.4

Human Toll Like Receptor 5 (TLR5) ELISA Kit
RD-TLR5-Hu-48Tests	Reddot Biotech	48 Tests	EUR 600

Human Toll Like Receptor 5 (TLR5) ELISA Kit
RD-TLR5-Hu-96Tests	Reddot Biotech	96 Tests	EUR 830.4

The relative expression of pro-inflammatory (IL6 and TNF) and anti-inflammatory / immunosuppressive cytokine genes (IL-10 and TGF beta1) qPCR.Results examined by Real-time: We found that the MDA-MB-468 cells expressed TLR2, TLR3, TLR6, TLR8 and TLR9 gene and T47D cells express TLR3 gene, TRL5, TLR8 and TLR9. In vitro stimulation with CpG TLR9 significantly reduce cell viability T47D and MDA-MB-468 cells.