Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro

Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro

Traumatic optic neuropathy is a common clinical problem. Damage to the optic nerve leads to shear stress and secondary triggers swelling in the optic canal. Objective studies to explore the role of the inflammatory response after optic nerve injury (ONI) in toll-like receptor-9 knockout mice (TLR-9 – / -) mice compared with wild-type (WT). At first, the TLR-9 – / – and WT mice were subjected to ONI. We later found out that the ONI significantly up-regulated the expression of TLR-9 levels in retinal tissue of WT mice.

Retinal degeneration after ONI was relieved in the TLR-9 – / – mice, as evidenced by an increase in the number of retinal ganglion cells (RGCs) and the thickness of the inner retinal layer (IRL). TUNEL staining and immunofluorescence staining of BRN3A show that the TLR-9 KO effectively improve the survival of RGCs. ONI-enhanced expression of Iba-1 and TMEM119 was markedly reduced in TLR-9 – / – mice, indicating suppression of the activation of microglia.

In addition, the production of pro-inflammatory regulator, including inducible nitric oxide synthase (iNOS), macrophage chemo-attractant protein (MCP) -1, cyclooxygenase-2 (COX-2), interleukin (IL) -1β, IL-18 and tumor necrosis factor-α (TNF-α), significantly decreased the TLR-9 – / – mice following ONI. TLR-9 KO-attenuated inflammation especially through pressing myeloid differentiation factor 88 (MyD88) and IL-1 receptor associated kinase 4 (IRAK4). Furthermore, ONI highly up-regulated protein expression levels of phosphorylated (p) -IKKα, p-p-IκBα and nuclear factor (NF) -κB, while being pressed on TLR-9 – / – mice. Effect of TLR-9 at ONI verified in lipopolysaccharide (LPS) -stimulated retinal microglia cells transfected with small interfering RNA TLR-9 (siTLR-9).

As expected, promote TLR-9 agonist real restored with inflammation in TLR-9 knockdown cells stimulated by LPS. Therefore, all the above findings indicate that suppress TLR-9 shows the neuroprotective effects against ONI through the reduction of inflammatory responses, and TILR-9 may be a promising therapeutic targets to develop effective strategies for the treatment of optic neuropathy.

Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro
Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro

Insight into the sequence-structure relationship Toll / Interleukin-1 receptor TLR cytoplasmic domain of the understanding of the function of TLR 2 heterodimer conserved in mammals

Signal response of TLR2 to the ligand always as homodimers or heterodimerization with TLR1 / TLR6. Toll / Interleukin-1 receptor (TIR) ​​domain of the cytoplasmic region of TLR set dimerization and interaction with an adapter molecule to establish an active signaling complex. To understand the function of TLR2 conservation-heterodimers between distantly related species of human (h) and mouse (m), TIR-TIR interaction patterns in heterodimers have been learned through the order-structural point of view.

comparative analysis of primary sequence and structural patterns of TLRs (1/2/6) strengthen higher sequence homology between TLR1 and TLR6. docking analysis of molecules TLR2-TLR1 and TLR2-TLR6 dimer cytoplasm in both mice and humans have identified that for the interaction loop BB / near-BB residue loop TLR2 involved with near-DD loop TLR1 and DD residue loop TLR6 in the domain of TIR, which can cause differential signal

Mouse Toll Like Receptor2 ELISA Kit

MBS032058-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor2 ELISA Kit

MBS032058-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor2 ELISA Kit

MBS032058-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor2 ELISA Kit

MBS032058-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor4 ELISA Kit

MBS026966-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor4 ELISA Kit

MBS026966-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor4 ELISA Kit

MBS026966-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor4 ELISA Kit

MBS026966-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor2 ELISA Kit

MBS733440-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Toll Like Receptor2 ELISA Kit

MBS733440-48StripWells 48-Strip-Wells
EUR 485

Mouse Toll Like Receptor2 ELISA Kit

MBS733440-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Toll Like Receptor2 ELISA Kit

MBS733440-96StripWells 96-Strip-Wells
EUR 690

Mouse Toll Like Receptor4 ELISA Kit

MBS732114-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Toll Like Receptor4 ELISA Kit

MBS732114-48StripWells 48-Strip-Wells
EUR 485

Mouse Toll Like Receptor4 ELISA Kit

MBS732114-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Toll Like Receptor4 ELISA Kit

MBS732114-96StripWells 96-Strip-Wells
EUR 690

Mouse Toll Like Receptor 9 ELISA

E01A25648 96T
EUR 700
Description: ELISA

Mouse Toll Like Receptor 5 ELISA

E01A25932 96T
EUR 700
Description: ELISA

Mouse Toll Like Receptor 6 ELISA

E01A25933 96T
EUR 700
Description: ELISA

LncRNA Profiler Complete qPCR Array Kit (cDNA synthesis kit, qPCR array and SYBR Green reagent) 20 profiles

RA910A-1 20 profiles
EUR 1329.6

Recombinant Mouse Toll Like Receptor 2

MBS147219-0001mg 0.001mg
EUR 240

Recombinant Mouse Toll Like Receptor 2

MBS147219-0005mg 0.005mg
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Recombinant Mouse Toll Like Receptor 2

MBS147219-005mg 0.05mg
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Recombinant Mouse Toll Like Receptor 2

MBS147219-5x005mg 5x0.05mg
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Mouse Toll Like Receptor 3 ELISA kit

E01A25641 96T
EUR 700
Description: ELISA

Mouse Toll Like Receptor 7 ELISA kit

E01A25645 96T
EUR 700
Description: ELISA

Mouse Toll Like Receptor 8 ELISA kit

E01A25646 96T
EUR 700
Description: ELISA

Mouse Toll Like Receptor 3 ELISA kit

E03T0066-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 3 ELISA kit

E03T0066-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 3 ELISA kit

E03T0066-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 2 ELISA kit

E03T0068-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 2 ELISA kit

E03T0068-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 2 ELISA kit

E03T0068-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 7 ELISA kit

E03T0070-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 7 ELISA kit

E03T0070-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 7 ELISA kit

E03T0070-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 8 ELISA kit

E03T0071-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 8 ELISA kit

E03T0071-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 8 ELISA kit

E03T0071-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 8 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 9 ELISA kit

E03T0073-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 9 ELISA kit

E03T0073-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 9 ELISA kit

E03T0073-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 5 ELISA kit

E03T0755-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 5 ELISA kit

E03T0755-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 5 ELISA kit

E03T0755-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 5 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 6 ELISA kit

E03T0756-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 6 ELISA kit

E03T0756-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 6 ELISA kit

E03T0756-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Toll Like Receptor 6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Toll Like Receptor 1 ELISA Kit

MBS105595-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 1 ELISA Kit

MBS105595-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 1 ELISA Kit

MBS105595-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 1 ELISA Kit

MBS105595-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 7 ELISA Kit

MBS006510-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 7 ELISA Kit

MBS006510-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 7 ELISA Kit

MBS006510-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 7 ELISA Kit

MBS006510-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 5 ELISA Kit

MBS055961-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 5 ELISA Kit

MBS055961-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 5 ELISA Kit

MBS055961-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 5 ELISA Kit

MBS055961-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 9 ELISA Kit

MBS018067-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 9 ELISA Kit

MBS018067-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 9 ELISA Kit

MBS018067-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 9 ELISA Kit

MBS018067-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 8 ELISA Kit

MBS027553-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 8 ELISA Kit

MBS027553-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 8 ELISA Kit

MBS027553-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 8 ELISA Kit

MBS027553-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 10 ELISA Kit

MBS081732-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 10 ELISA Kit

MBS081732-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 10 ELISA Kit

MBS081732-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 10 ELISA Kit

MBS081732-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 6 ELISA Kit

MBS085675-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 6 ELISA Kit

MBS085675-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 6 ELISA Kit

MBS085675-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 6 ELISA Kit

MBS085675-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 3 ELISA Kit

MBS037604-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Toll Like Receptor 3 ELISA Kit

MBS037604-48StripWells 48-Strip-Wells
EUR 550

Mouse Toll Like Receptor 3 ELISA Kit

MBS037604-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Toll Like Receptor 3 ELISA Kit

MBS037604-96StripWells 96-Strip-Wells
EUR 765

Mouse Toll Like Receptor 1 ELISA Kit

IMSTLR1KT each
EUR 718
Description: Mouse Toll Like Receptor 1 ELISA Kit

Mouse Toll Like Receptor 3 ELISA Kit

IMSTLR3KT each
EUR 718
Description: Mouse Toll Like Receptor 3 ELISA Kit

Mouse Toll Like Receptor 4 ELISA Kit

IMSTLR4KT each
EUR 684
Description: Mouse Toll Like Receptor 4 ELISA Kit

Mouse Toll Like Receptor 6 ELISA Kit

IMSTLR6KT each
EUR 684
Description: Mouse Toll Like Receptor 6 ELISA Kit

Mouse Toll Like Receptor 7 ELISA Kit

IMSTLR7KT each
EUR 718
Description: Mouse Toll Like Receptor 7 ELISA Kit

Mouse Toll Like Receptor 5 ELISA Kit

MBS7256422-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Toll Like Receptor 5 ELISA Kit

MBS7256422-48StripWells 48-Strip-Wells
EUR 485

Mouse Toll Like Receptor 5 ELISA Kit

MBS7256422-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Toll Like Receptor 5 ELISA Kit

MBS7256422-96StripWells 96-Strip-Wells
EUR 690

Mouse Toll Like Receptor 6 ELISA Kit

MBS7256423-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Toll Like Receptor 6 ELISA Kit

MBS7256423-48StripWells 48-Strip-Wells
EUR 485

Mouse Toll Like Receptor 6 ELISA Kit

MBS7256423-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Toll Like Receptor 6 ELISA Kit

MBS7256423-96StripWells 96-Strip-Wells
EUR 690

Mouse Toll Like Receptor 9 ELISA Kit

MBS724122-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Toll Like Receptor 9 ELISA Kit

MBS724122-48StripWells 48-Strip-Wells
EUR 485

Mouse Toll Like Receptor 9 ELISA Kit

MBS724122-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Toll Like Receptor 9 ELISA Kit

MBS724122-96StripWells 96-Strip-Wells
EUR 690

Mouse Toll Like Receptor 7 ELISA Kit

MBS724492-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Toll Like Receptor 7 ELISA Kit

MBS724492-48StripWells 48-Strip-Wells
EUR 485

Mouse Toll Like Receptor 7 ELISA Kit

MBS724492-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Toll Like Receptor 7 ELISA Kit

MBS724492-96StripWells 96-Strip-Wells
EUR 690

Mouse Toll Like Receptor 3 ELISA Kit

MBS747112-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Toll Like Receptor 3 ELISA Kit

MBS747112-48StripWells 48-Strip-Wells
EUR 485

Mouse Toll Like Receptor 3 ELISA Kit

MBS747112-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Toll Like Receptor 3 ELISA Kit

MBS747112-96StripWells 96-Strip-Wells
EUR 690

Mouse Toll Like Receptor 8 ELISA Kit

MBS748656-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Toll Like Receptor 8 ELISA Kit

MBS748656-48StripWells 48-Strip-Wells
EUR 485

Mouse Toll Like Receptor 8 ELISA Kit

MBS748656-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Toll Like Receptor 8 ELISA Kit

MBS748656-96StripWells 96-Strip-Wells
EUR 690

Toll Like Receptor 2 Mouse Recombinant

rAP-4336 Inquiry Ask for price

Mouse Toll Like Receptor 3 (TLR3) Protein

20-abx069362
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Mouse Toll Like Receptor 3 (TLR3) Protein

20-abx069363
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Mouse Toll Like Receptor 3 (TLR3) Protein

20-abx069364
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Mouse Toll Like Receptor 4 (TLR4) Protein

20-abx069366
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Mouse Toll Like Receptor 6 (TLR6) Protein

20-abx069372
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Mouse Toll Like Receptor 1 (TLR1) Protein

20-abx168804
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Mouse Toll Like Receptor 5 (TLR5) Protein

20-abx168806
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Mouse Toll Like Receptor 9 (TLR9) Protein

20-abx168412
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Mouse Toll Like Receptor 7 (TLR7) Protein

20-abx168450
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Mouse Toll Like Receptor 2 (TLR2) Protein

20-abx167213
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Mouse Toll Like Receptor 2 (TLR2) Protein

abx167213-100g 100 µg
EUR 537.5

Mouse Toll Like Receptor 2 (TLR2) Protein

abx167213-10g 10 µg
EUR 212.5

Mouse Toll Like Receptor 2 (TLR2) Protein

abx167213-50g 50 µg
EUR 375

Mouse Toll Like Receptor 9 (TLR9) Protein

abx168412-100l 100 µl
EUR 225

Mouse Toll Like Receptor 9 (TLR9) Protein

abx168412-1ml 1 ml
EUR 587.5

Mouse Toll Like Receptor 9 (TLR9) Protein

abx168412-200l 200 µl
EUR 400

Mouse Toll Like Receptor 7 (TLR7) Protein

abx168450-1ml 1 ml
EUR 225

Mouse Toll Like Receptor 1 (TLR1) Protein

abx168804-1ml 1 ml
EUR 187.5

Mouse Toll Like Receptor 5 (TLR5) Protein

abx168806-1ml 1 ml
EUR 212.5

Mouse Toll Like Receptor 3 (TLR3) Protein

abx069362-10mg 10 mg
EUR 225

Mouse Toll Like Receptor 3 (TLR3) Protein

abx069362-50mg 50 mg
EUR 400

Mouse Toll Like Receptor 3 (TLR3) Protein

abx069363-25mg 25 mg
EUR 400

Mouse Toll Like Receptor 3 (TLR3) Protein

abx069363-5mg 5 mg
EUR 225

Mouse Toll Like Receptor 3 (TLR3) Protein

abx069364-10mg 10 mg
EUR 225

Mouse Toll Like Receptor 3 (TLR3) Protein

abx069364-50mg 50 mg
EUR 400

Mouse Toll Like Receptor 4 (TLR4) Protein

abx069366-25mg 25 mg
EUR 337.5

Mouse Toll Like Receptor 4 (TLR4) Protein

abx069366-5mg 5 mg
EUR 200

Mouse Toll Like Receptor 6 (TLR6) Protein

abx069372-100g 100 µg
EUR 225

Mouse Toll Like Receptor 2 (TLR2) Protein

abx692566-100g 100 µg
EUR 837.5

Mouse Toll Like Receptor 2 (TLR2) Protein

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Mouse Toll Like Receptor 2 (TLR2) Protein

abx680018-100g 100 µg
EUR 225

Mouse Toll Like Receptor 2 (TLR2) Protein

abx680018-200g 200 µg
EUR 325

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

20-abx190547
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  • 96 tests

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

20-abx190582
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  • 96 tests

Mouse Toll Like Receptor 7 (TLR7) CLIA Kit

20-abx493285
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  • 96 tests

Mouse Toll Like Receptor 1 (TLR1) CLIA Kit

20-abx493339
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  • 96 tests

Mouse Toll Like Receptor 2 (TLR2) CLIA Kit

20-abx491847
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  • 96 tests

Mouse Toll Like Receptor 6 (TLR6) CLIA Kit

20-abx491879
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  • 96 tests

Mouse Toll Like Receptor 9 (TLR9) CLIA Kit

20-abx491922
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  • 10 × 96 tests
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  • 96 tests

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

EKN50884-48T 48T
EUR 426.72

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

EKN50884-5x96T 5x96T
EUR 2895.6

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

EKN50884-96T 96T
EUR 609.6

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

EKN51078-48T 48T
EUR 426.72

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

EKN51078-5x96T 5x96T
EUR 2895.6

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

EKN51078-96T 96T
EUR 609.6

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

EKU09773-48T 48T
EUR 685.72

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

EKU09773-5x96T 5x96T
EUR 4653.1

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

EKU09773-96T 96T
EUR 979.6

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

EKU09967-48T 48T
EUR 685.72

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

EKU09967-5x96T 5x96T
EUR 4653.1

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

EKU09967-96T 96T
EUR 979.6

Mouse Toll Like Receptor 4 (TLR4)CLIA Kit

SCA753Mu-10x96wellstestplate 10x96-wells test plate
EUR 6965.86
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 4 (TLR4) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Toll Like Receptor 4 (TLR4)CLIA Kit

SCA753Mu-1x48wellstestplate 1x48-wells test plate
EUR 678.84
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 4 (TLR4) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Toll Like Receptor 4 (TLR4)CLIA Kit

SCA753Mu-1x96wellstestplate 1x96-wells test plate
EUR 918.34
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 4 (TLR4) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Toll Like Receptor 4 (TLR4)CLIA Kit

SCA753Mu-5x96wellstestplate 5x96-wells test plate
EUR 3772.51
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 4 (TLR4) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

4-SCA753Mu
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 4 (TLR4)Serum, plasma, tissue homogenates and other biological fluids

Mouse Toll Like Receptor 3 (TLR3)CLIA Kit

SCB989Mu-10x96wellstestplate 10x96-wells test plate
EUR 6965.86
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 3 (TLR3) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Toll Like Receptor 3 (TLR3)CLIA Kit

SCB989Mu-1x48wellstestplate 1x48-wells test plate
EUR 678.84
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 3 (TLR3) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Toll Like Receptor 3 (TLR3)CLIA Kit

SCB989Mu-1x96wellstestplate 1x96-wells test plate
EUR 918.34
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 3 (TLR3) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Toll Like Receptor 3 (TLR3)CLIA Kit

SCB989Mu-5x96wellstestplate 5x96-wells test plate
EUR 3772.51
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 3 (TLR3) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

4-SCB989Mu
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Mouse Toll Like Receptor 3 (TLR3)Serum, plasma, tissue homogenates and other biological fluids

Mouse Toll Like Receptor 9 (TLR9) CLIA Kit

abx197813-100l 100 µl Ask for price

Mouse Toll Like Receptor 9 (TLR9) CLIA Kit

abx197813-50l 50 µl
EUR 618.75

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

MBS2000636-10x96StripWells 10x96-Strip-Wells
EUR 6315

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

MBS2000636-24StripWells 24-Strip-Wells
EUR 415

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

MBS2000636-48StripWells 48-Strip-Wells
EUR 640

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

MBS2000636-5x96StripWells 5x96-Strip-Wells
EUR 3480

Mouse Toll Like Receptor 3 (TLR3) CLIA Kit

MBS2000636-96StripWells 96-Strip-Wells
EUR 865

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

MBS2000860-10x96StripWells 10x96-Strip-Wells
EUR 6315

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

MBS2000860-24StripWells 24-Strip-Wells
EUR 415

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

MBS2000860-48StripWells 48-Strip-Wells
EUR 640

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

MBS2000860-5x96StripWells 5x96-Strip-Wells
EUR 3480

Mouse Toll Like Receptor 4 (TLR4) CLIA Kit

MBS2000860-96StripWells 96-Strip-Wells
EUR 865
.

Dimeric molecular dynamics simulations for both human and rat species recognize that a stable interface between the near-BB / BB circle discrete region of TLR2 and close-loop region DD and DD TLR1 and TLR6 each. Dimerization patterns observed in both species is further supported by Alanine scanning mutation studies.

Sierra

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